Objective To explore the effects of acupuncture and balance facilitation of muscular tension on the early rehabilitatio n of patients with stroke and hemiplegia.Methods Divided the 96 patients with acute stroke hemiplegia into group A and Brandomly(group B as control) Evaluate the rehabilitation before and after therapy,and deal with the data in statistics.The courses are 26 t 28 days.In group A.stab negative channel and points of upper limb as well as positive channel and points of lower limb of paralysis side in flaccid paralysis tage,After the muscular tension resumed,stab positive points of upper limb and negative points of lower limb,and try to recover the balance of muscular tension,and avoid muscular spasm to establish normal moving pattern,Results Compared with control group,group A hac prominent difference on the process of musculwar tension resuming.Incidence rate of muscular spasm,the ration of reeducing of neurologic impairment scores and increasing of motor function integral(FMA),MBI of the ability of daily life(ALD)as well as index of quality of life(QLI),P<0.01, Conclusion A cuppuncture and balance facillitation of muscular tension are useful in the early rehabilitation in hemiplegia.
Objective To study the recognition,recall and everyday memory in patients with Parkinson‘s dissease,Methods 16 patients with idiopathic PD and 16 matched healthy control were examined using eight subtests of Multiple Memory Assessment Scale(MMAS)-word recall,picture recall,picture reproduction,picture recognition,wored recognition and everyday memory,Results Except for word recognition(P>0.0t),the performances of patients were significantly worse in picture recall(P<0.05),word recall(P<0.01),picture reproduction(P<0.01),picture recognition(P<0.01),and everyday memory(P<0.01)than those of mormal control.The most memory performances of patients with Parkinson‘s disease were significantly negatively correlated with the score of Yale Extapyramidal Symptom Scale(YESS).Conclusion The picture recognition,recall,and everyday memory of PD patients were impaired,and the impairment was related to the deficient function of the striatofrontal circuit.
Objective To construct transgenic vectors of mouse DSP.Methods T construct pcDNA3.1-CX by substituting CMV promoter of pcDNA3.1 with promoter cβ-actin,and establish the ultiate transgenic vector by cloning DSP coding sequence into pcDNA3.1-CX.Result Enzyme digestion and sequencing ae consistent with expected.Conclusion The transgenic vector of mouse DSP was constructed successfully.
Objective To evaluate the usefulness of diffusion-tensor MR imaging in brain white matter diseases.Methods A combined conventional and diffusion tensor MRI were obtained from 10 multiple selerosis,10 multiple lacunar infarction,3 cysticercosis,1 angiitis, 1morphinist and 10 healthy control volunteers.After oblaining mean diffusivity (D) and fractional anisotropy images and image coregistration,the corelations of the lesions and the white matter pathways were investigated.D and A values were measured form four big lesions which can be seen in T2WI and compared to contralateral white matter.Also D and AI value of four different anatomic locations of normal-appearing white matter regions were measured in all patients and controls.Results Whereas the lesions of infarction,cysticercosis and angiitis were in and outside the white matter pathways,all plaques of multiple sclerosis were inside the whit matter pathways.The brain white matter lesions by 1 morphinist were beside the lateral ventricle with big pachy appearance,which was partly inside white matter.For MS,D value was higher in lesion than contorl white matter. But for other diseases,D value could be seen higher or lower compared to healthy side.Ai values were lower in all lesions,D valuewas higher and AI was lower in normal appearing brain white matter when comparing MS to other cases or healthy control volunteers.Conclusion Diffusion tensor MR images can determine the correlations of the lesions and brain white matter pathways.The changes of D and AI values can improve specificity in differential diagnoses though quanti6tatively analyzing the tissue damage in lesions and normal-appearing brain white matter.
Objective To investigate the effects of flunarizine on HSP70 gene expression for following transient ischemia.Methods Northern blot and immunohistochmistry(IHC)were used to determine the expression of the HSP70 during different periods after post-ischemic reperfusion with or without Flunarizine treatment in the gerbil.Results The HSP70mRNA expression was increased in the forebrain,but the HSP70 protein only expressed at the l st day of reperfusiong(P<0.05);Flunarizine treatment could increase the expression of HSP70 protein,but couldn‘t significantly increase the expression of HSP70 mRNA(P>0.05).Conclusion Flunarizine could protect neurons from ischemic damage through increasing the HSP70 expression.
Objective To explore the possibility of diagnosis types of acute stroke,elevating treatment quality and promoting prognosis with acute stroke clinical measuring scale.Methods To gain a measuring scale formula and simplify this formula after stepwise regression Fisher distinguish analysis to 18 clinical variable of 184 acute stroke patients and to validate its sensitivity,specificity and positive foretell value to diagnosis of acute stroke,Results We gained scale that Y=0.617×action+0.4856×BP＋1.241×headache+0.74×vomiting+0.955×cervical resistance-1.215×TIA－0．727×heart disease-2.78;sensitivity of this formuta to diagnosis of cerebral infarction and cerebral hemorrhage was 90.5% and 70% respectively,its specificity was 70% and 90.5% respectively,positive foretell value was 71.7% and 89.7%(Y≥ 0 means cerebral hemorrhage,Y<0 means cerebral infarction).Simple formulta is S=0.5×action+0.5×BP+1×headache+1×vomiting+1×cervical resistance-1×TIA－1×hear disease-3;its sensitivity was 89.3% and 68%,specificity was 68% and 89.3%,positive foretell value was 70.1% and 88.3%,There was no apparent difference in sensitivity;specificity and positive forelell value between two formulas.Conclusion Acute stroke clinical measuring scale can help early diagnosis,treatment and rehabilitation of cerebral stroke patients.
Objective To investigate relationship between elderly dementia and plasma homocysteine level.Method 69 patients with elderly dementia(ED)and 69 heathy seniles were selected and their plasma homocysteine(Hcy)level was determined by high-performance liquid chromatography and fluorescene detector.Result Plasma Hcy level in study was (26.5±11.8)μmol/L while in control group it was(12.4±2.4)μmol/L,(P<0.001).Conclusion Higher plasma Hcy level could be a risk factor to the onset of ED.
Objective To study the relationship between traditional Chinese medicine(TCM)syndrome and serum level of IGF-1 and IGFBP-3 in patients with acut cerebral infarction(ACI).Methods 75 patients of ACI were divided into two groups by TCM‘s syndrome differentiation:apolexy involving the channels(AIC)and apolexy involving the viscera(AIV).Serum level of IGF-1 and IGFBP-3 was detected by ELISA di-antibody clipping technique(DACT) and was compared with that of 30 normal controls,Results Serum level of IGF-1 and IGFBP-3 in AIC group and AIV group were significantly different from control groups;and differences between AIC group and AIV group were statistically significant.Serum level of IGF-1 and IGFBP-3 in all syndromes of AIC group AVI group were remarkably lower than control group.Among them,syndrome of Yin-deficiency of liver and kidney and sthenia liver-yang an syndrome of blood stasis due to Qi deficiency had lower serum level of IGF-1 and IGFBP-3 than syndrome of empty and obstruction of channel.So did collapse syndrome and syndrome of mental disorder due to phlegm-fire to syndrome of wind-fire evil lucid orifices and block Yin syndrome.Conclusion There are to some extent correlation with TCM‘s Syndrome and serum level of IGF-1 and IGFBP-3 in patients with ACI.Serum level of IGF-1 and IGFBP-3 might be microcosmic referent markers of the damage of Qi and Yin by TCM‘s syndrome differentiation.
Objective To explore the relationship between diabetes and psychology factors.Methods We investigated 64 patients of diabetes type 2 with EPQ score of character,SCL-90 score of the symptom and the score of socidal support,and compared the scores with that of control group.Results The SXL-90 score of diabetics was higher than that of control group remarkably(P<0.010,score of social support of diabetics was lower than that of control group(P<0.001).Conclusion The psychological factor play a proper role in the generation and development of diabetes.It is worth further study and should be paid more attention.
Objective To study the effect about walk traning of cerebral palsy treatment with conductive education approach and Bobath method.Methods 86 patients with cerebral palsy were divided into two groups.Teated with conductive education approach and Bobath methoa,Effects was evaluated before and after the treatment.Results The overall score on motion function development was not significantly eifferent between the two groups(P>0.5).However,There were significantly different in walking established and gait improved in the two groups(P<0.05).Conlusion Both of the two therapeutic methods are effective in treating cerebral palsy.However,conductive education approach is more effectual in walking established and gait improved.
Objective To release the heroin addicts‘ sufferings,we made rapid opiate detoxification by injecting naloxine under the general anesthesia.Method 160 volunteers were divided at randon into two groups:Group A were performed under the combined anesthesia with propofol,midazolam and kelamine.Group B were performed under the combined anesthesia with propofol with midazolam and tramadol.The vital signs were recorded and the withdrawal syndrome of the volunteers were assessed during the whole process.Result All of the withdrawal symptoms scores 24 hours after ROD in group B were lower than its pre-treatment;The symptoms of the thirs,tsleeping disturbance,nausea and vomiting,skeletal muscular pains and anorexia scores in group A were also lower than its pre-treatment;and no too much differeence belween group A and group B.But tearing,anxiety and diarrhea scores in group A were almost the same as the pre-treatment and higher than group B.Both groups received of the naloxone treatment smoothly,and remained in the hospital for about 3 days.Conclusion The effect of rapid opiate detoxification of naltrexone with the ketamine or tramadol under anesthesia is obvious.The tramadol is better than others.