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  • Rehabilitation of mental disturbance in patients with stroke 免费阅读 下载全文
  • Utilization of systemic planned health education in the rehabilitation of hypertension patients 免费阅读 下载全文
  • According to modern health opinion,patients‘ good compliance has close relationship with patients‘ health faith and knowledge.So practicing health education and synthetictherapy accompanied with drug treatment benefits control and rehabilitation of disease.OBJECTIVE:To investigate the effects of systemic planned health education on the rehabilitation of hypertension patients.UNIT:Department of Rehabilitation,Qindu Hospital of Forth Military Medical University.SUBJECTS:234 hypertension cases treated between January 2000 and December 2000(168 males and 66 females),age 42-81.all the cases accorded with the WHO/ISH hypertension diagnosis criteris.Education degree:159 cases were above senior high school,and 75 cases were below junior high school (including 4 illiteracies).
  • Correlation research between the patients with cerebral infarction in different ages and blood lipid levels 免费阅读 下载全文
  • AIM:To investigate the relationship between the patients with cerebral infarction(CI)in different ages and blood lipid levels.METHODS:The serum concentration of blood lipid levels were measured in 211 patients with CI and 144 control cases.RESULTS:The level of lipoprotein(a)[Lp(a)] in the young adults with CI and the levels of triglyceride(TG),total cholesterol(TC),low-density lipoprotein-cholesterol(LDL-C),apolipoproteinB100(ApoB100) and Lp(a) in the subgroup of mid-adults with CI were much higher than corresponding controls.The levels of TC,LDL-C ApoB100 and Lp(a) in the subgroup of olds were significantly higher when compared with the corresponding controls,while the high-density lipoprotein-cholesterol(HDL-C) level was lower.Multiple linear regression showed that age had positive correlation to TC and ApoB100 and negative correlation to HDL-C.CONCLUSION:There are different disturbances of blood lipid metabolism in the patients with CI in different ages.The serum Lp(a) levels may be an independent risk factor for CI.
  • Clinical analysis of 52 cases of epilepsy after stroke 免费阅读 下载全文
  • There are many causes of epilepsy and stroke is the common reason of delayed epilepsy especially after formation of throbosis and multiple lacunar cerebral infarction^[1].
  • Alternation of plasma c-type natriuretic peptide in cerebral infarction 免费阅读 下载全文
  • AIM:To investigate the Effects of c-type natriuretic peptide(CNP) on cerebral infarction.METHODS:Plasme levels of CNP were concomitantly measured by radioimmunoassay in 30 patients with cerebral infarction and in 30 normal controls.RESULTS:Plasma levels of CNP were increased significantly in the acute stage of cerebral infarction than those in the normal controls(P<0.01) and levels in the moderate and serious cases were lower than those in the slight cases(P<0.01).CONCLUSION:IN cerebral infarction the increase of plasma CNP was in accordance with the severity of the disease.CNP in the pathophsiology of acute cerebral ischemia had a deleterious effect on the evolution of cerebral infarction.
  • The protective effect of subhypothermiaon brain of patient with ischemic cerebrovascular disease on different time 免费阅读 下载全文
  • The subhypothermia treatment presents the advantages of decreasing energy metabolism and consumption of lactic acid,reducing release of active amino acid and alleviating inflammatory brain injury by cerebrovascular disease protecting blood-cerebral barrier and stabilize permeability of vessel.OBJECTIVE:To observe the effect of Subhypothermia on brain of patient with acute and severe ischemic cerebrovascular disease in recovery period on different time.
  • The recovery comparison of comprehensive rehabilitation and simple pharmacotherapy on the patients after stroke during the period of sequela 免费阅读 下载全文
  • Central nerve system has the ability of re-uniting of structure and function after injury that is high plasticity,which can be strengthened and consolidated through continuous studies and training.OBJECTIVE:To investigate the effect of comprehensive rehabilitation and simple pharmacotherapy on the patients after stroke in recovery pariod.
  • Rehabilitation treatment of dysphagia in 81 cases of stroke 免费阅读 下载全文
  • Dysphagia is the common common complication in stroke,often leads to nutrition deficiency,asparition pneumonia,suffocation and at the same time the pessimism,despair,complicated reduce patients‘ living confidence that will influence entire therapeutic course.OBJECTIVE:To investigate the treating Methods of dysphagia in stroke.
  • The principle analysis of rehabilitation on 46 patients with cerebrovascular disease and secondary epilepsy 免费阅读 下载全文
  • Linguistic rehabilitation nursing of pregnancy-induced hypertension syndrome associated with cerebral hemorrhage 免费阅读 下载全文
  • Pregnancy-induced hypertension syndrome associated with cerebral hemorrhage is the common cause of obstetric death and even emergency treatment succeeds,living quality is affected because of lalopathy.OBJECTIVE:To explore effect of linguistic rehabilitation of pregnancy-induced hypertension syndrome associated cerebral hemorrhage.
  • The effect of early enteral nutritive support on patients after esophageal and gastric operation 免费阅读 下载全文
  • AIM:To investigate the availability and safety of early enteral nutritive support after esophageal and gastric operation.METHODS:The postoperative patients of esophageal and gastric operation were randomly divided into enteral nutrition(EN) group(n=20) and parenteral nutrition(PN) group(n=20) and were given nutritive support of same ammoni and same quantity of heat after postoperative 24 hours,continuously for 7 days.RESULTS:The patients of both groups recovered and were discharged after treatment.The assessing index of nutrition of EN group was better than PN group (see table of clinical index).And the hospitalization fees of EN group were lower than PN group.The time of hospitalization of EN group was also shorter than PN group.CONCLUSION:Early enteral nutritive support after esophageal and gestric operation was safety and the rehabilitation effect was obvious and had extensive clinical application values.
  • Infertious risk factors analysis to senile patients with diabetes 免费阅读 下载全文
  • Incidence of diabetes combined with infection was very high,disease condition was serious,course of disease was long which made treatment very difficult^[1-3].Senile diabetes were more easy to be infected because of bad control effect of blood glucose and decreased immune function and the infection was difficult to control.Corresponding risk factors about senile diabetes combined with infection were analyzed in this article to make timely diagnosis and treatment.
  • Radioimmunological analysis of pressure regulating substances and their relationship with primary and renal hypertension 免费阅读 下载全文
  • Effect of Renin-angiotension-aldosterone system(RAS) in onset of hypertension has been clear,but the relationship between 7 kinds of pressure regulating substances and primary and renal hypertension(HP) need a further study.OBJECTIVE:To explore the effects and significance of RAS,endothelin(ET),Nitric oxide(NO),neuropeptide Y(NPY),ralcitonin gene-related peptides(CGRP) in primary and renal hypertension.
  • Influence of changing bad living habits on blood pressure control of hypertension patients 免费阅读 下载全文
  • Living habits with smoking,obesity and rest is high risk factor of hypertension.Every hypertension patient including those receiving drug therapy should change living habit.When living habit ameliorate,decompression function can be observed and risk factors of hypertension decrease.OBJECTIVE:To investigate Influence of changing bad living habits on blood pressure control of hypertension patients.UNIT:Department of Cardiology Internal Medicine of Second People‘s Hospital of Wenzhou.SUBJECTS:173 hypertension cases from September 1999 to June 2001,who accord with WHO diagnosis criteria issued 1999,including 129 males and 44 females,age 32-93,average age 67.INTERVENTION:Except for routine drug therapy,all the patients received health education,which focus on changing bad living habits,including:(1)Mental instruction:Some studies showed that modd of patients with hypertension was unstable,interpersonal relationship was sensitive or combined with anxiety,depression and paranoid.To this kind of patients,we adopted mental dredging,relaxing therapy,listening music,setting up their insterestings,et al,to change their mood,encourage patients to actively take part in all kinds of beneficial activities,keep calm,avoid exiting of mood,train self-control ability and keep good mental state.(2)Guide diet:restrict salt,high cholesterol,high fat diet and supply proper potassium,calcium and magnesium.Everyday intake of sodium should be less than 6g,fried foods and visceral of animal should be reduced,fruits containing more potassium such as orange,banana were eaten to control hypertension.Diets should contain vitamins,superior protein,calcium,Mg such as milk,fishes,musroom,vegetables,fruits.vitamins could promote metabolism of lipoids,especially that vitamin C could decrease catelone level.Ca,Mg also did good to decreasing of blood pressure.(3) Control weight:45 cases combined with obesity control weight.(4)Stop smoking and drinking.(5)Construct good living habit,take media and low strength exercise such as walk,jog,riding bicycle and gymnastics.Every patient take exercises 3-5 times every week with about half an hour for each time.RESULT:In these 173 cases,157 cases master self-care knowledge and health living habit and BP was under control.BP of 59 cases were fluctuating,after psychic nurse and removal of bad habits,BP was well controlled.CONCLUSION:Changing bad living habits play important function on blood pressure control of hypertension patients.
  • Electrocardiogram reaction of coronary heart disease after hyperbaric oxygen treatment 免费阅读 下载全文
  • Electrocardiogram(ECG)reaction of patients with coronary heart disease(CHD) are not improved markedly by medical therapy,but the patients‘ S-T,T of ECG are improved obviously by HBO therapy.OBJECTIVE:To observe the change of ECG of patients with CHD treated by HBO.RESULTS:Obviously effective:S-T restored to isopotential line or electric pressure was less than 0.05 mV,T-wave restored to more than or equal to 1/10 R-wave,3 cases in HBO group,0 case in control group.Effective:Electric pressure of S-T decreased to more than or equal to 0.5mV,t-wave changed from double-direction to upright or from low-level to upright,but less than 1/10 R-wave,4 cases in HBO group,3 cases in control group.No effect:There were no ECG change,3 cases in HBO group,7 cases in control group.CONCLUSION:HBO can improve myocardial ischemia and hypoxia,thus ECG can be improved.
  • Preoperative psychoanalysis and nursing measures of senior patients with coronary heart disease in intervening treatment 免费阅读 下载全文
  • The intervening treatment of senior patients with coronary heart disease is more and more.It is important of preoperative psychoanalysis and nursing measures for the patients according to natural characteristics,educational extent and knowledge of diseases of senior patients.OBJECTIVE:To introduce psychological characteristics of patients with coronary heart disease and nursing measures.
  • Report of 2 cases with brachium potine syndrome 免费阅读 下载全文
  • Brachium potine syndrome is also called potine cerebellum lesion syndrome,is localized at facial,acoustic,trigeminal and vestibule nerve roots.In clinic,lesion in this zone is rare.We met two cases recently.Both of cases were acute onset,with hypertension history.First symptoms were dizziness,unstability of gait,facial hemianesthesia,comeal reflex dullness,poor hearing and dystaxia.Cerebral MRI showed brachium potine with long T1 and T2,signal of focus with clear margin,enhance scan showed slight or apparent reinforcement.To determine in what degree to treat them and how to use method of evidence-based medicine to determine their diagnosis and best therapy,we spent less than 3 hours on searching and gaining evidences through computer of provincial medical information center.
  • The protective effect of ischemic preconditioning occur in patients with acute myocardiac infarction 免费阅读 下载全文
  • Ischemic preconditioning occur refers to the occurrence of many unstable angina pectoris before acute myocardial ischemia(AMI).It is generally recognized that ischemic preconditioning occur has protective effect on heart and can reduce infarction scope and improve contraction function of heart.Recently some authors whinks ischemic preconditioning occur will cause the exacerbation of patients‘ condition during the time of hospitalization and increase the incidence rate of angina and pectoris and death.OBJECTIVE:To explore the effect of ischemic preconditioning occur on prognosis of AMI.
  • Foot nursing of patients with diabetes 免费阅读 下载全文
  • Incidence of atherosclerosis was higher in patients with diabetes.Atherosclerosis of peripheral limbs mainly affect artery of lower limbs and abnormal feeling of foot and intermittent limping was the manifestation.To explore nursing methods of foot in patients with diabetes.
  • The rehabilitation effect of hyperbaric oxygenation on new-born with hypoxic and ischemic encephalopathy 免费阅读 下载全文
  • Hypoxic and ischemic encephalopathy (HIE) is a severe complication after asphyxia of new-born.It can cause death of new-born and also is an important reason for children‘ disablement.OBJECTIVE:To evaluate the effect of hyperbaric oxygenation on newborn with HIE.
  • External washing therakpy of traditional Chinese medicine to children's cerebral hypermyotonia 免费阅读 下载全文
  • Muscular tension of children with cerebral paralysis enhances and motor range of joint is limited,which directly affect motor function of children.Traditional Chinese medicine affirms the cause of cerebral paralysis is because of congenital feebleness,deficiency of liver-yin and kidney-yin and lack of proper care after birth.Deficiency of liver-yin and kindey-yin leads to lack of proper care of muscles and stagnancy of qi blood,marked by spasm of muscles and disadvantage of joint movement.OBJECTIVE:To explore the effect of decreasing musculartension,through washing therapy of traditional Chinese medicine accompanied with passive joint movements.
  • Analysis of mental health of students defeated in college entrance examination 免费阅读 下载全文
  • Although enrollment scale of College are amplifed every year,people are still very concerned about whether students are over line.The mental load of students under line is very heavy and their mental health is more to be worried.OBJECTIVE:To investigate state of mental health to students defeated in college entrance examination.
  • The analysis of depression in aged patients with myocardial infarction and its elative factors 免费阅读 下载全文
  • Depression occurrs in most aged patients with myocardial infarction,and the patients with longer disease courses,more severe disease,higher self estimation,lower education degree and fewer social support are often in more severe depression.OBJECTIVE:To study the depression in aged patients with myocardial infarction and its relative factors.
  • Mental nursing of community patients with psychosis in recovery stage 免费阅读 下载全文
  • Patients with mental disease gets into recovery stage after symptoms of acute phase are alleviated,returns to society and achieves clinical recovery.But some metal problems still exist in most patients that becomes an obstruction for patients to develop speciality and self-realization.OBJECTIVE:To explore mental nursing methods of community patients with mental disease in recovery stage.
  • The survey of the relationship between osteoporosis and relative effective factors in old men 免费阅读 下载全文
  • AIM:To measure the bone mineral density and the relative effective factors of osteoporosis in the different age groups,so as to study the relationship between both,and will offer the theoretical foundation on the prevention and treatment of osteoporosis in the old men.METHODS:Forearm bone mineral density were measured by dual energy X-ray absorptiometry (DEXA);By using full-automatic biochemical analytic instrument to measure serum calcium (Ca),phosphorus (P);By using radio-immunoassay to measure serum parathormone(PTH),Calcitonin(CT),1,25(OH2D3,25(OH)D3,interleukin-6(IL-6).Ninety-seven old men were divided into osteoporosis group and non-osteoporosis group,were compared with normal group of men under sixty years old.RESULTS:Some results such as bone mineral density,CT,1,25(OH)2O3 and 25(OH)D3 showed decrease,while some results such as serum PTH and IL-6 showed increase with aging.The former in osteoporosis proup were also significantly lower than those in non-osteoporosis group(P<0.05).The latter in osteoporosis group were also significantly higher than those in non-osteoporosis group(P<0.05-0.001).CONCLUSION;The change of the above relative effective factors lead to the following result.Bone resorption is increasing and bone formation is decreasing.These cause bone loss,at last,osteoporosis comes up.
  • Voice training to palatoschisis children 免费阅读 下载全文
  • Palatoschisis is a kind of congenital malformation.It can bring glossolalia to patients.If not treated in time,it would do harmful effects to patients‘ future.Besides general law of functional voice disorder,palatoschisis has its special characters.After examination and assessment,palatoschisis patients could improve their vocalization by voice training.OBJECTIVE:To observe the effects of voice training to vocalization of palatoschisis children.
  • Rehabilitative treatment of senile osteoporosis fracture 免费阅读 下载全文
  • When the senile patients with osteoporosis fracture are hospitalized,fracture is cured by surgical department of orthopedics and osteoporosis is cured by internal department of orthopedics,which is timely and appropriate.Even after union of fracture,the comprehensive treatment is essential for such patients.
  • Effect evaluation of artemisia desertorum spreng on ability of daily life after extraction of impacted tooth 免费阅读 下载全文
  • AIM:To investigate the effect of locally used Shahaosan on preventing the complication of extraction of impacted tooth.METHODS:274 cases patients with extraction of impacted teeth were randomly devided into 3 groups named A,B and C.Shahaosan and Yunnan white drug were grocessed into drug A and B by department of pharmacy with the same color,shape and quality which are blind to doctors and patients.When the impacted teeth were extracted,administed group A (92 cases) with drug A,group b(86 cases) with drug B and group c(96 cases) was a blank control.After the operation,incidence and severe intensity of dry socket in each group were observed and evaluated by scores.RESULTS:The incidence of dry socket in group a,B and C were 0.09%(1/92),2.32%(2/86),8.33%(8/96).There was no significant difference between group A and B,group b and C,while a significant difference showed between group A and C.The PoSSe score in group A,B and C was 19.36,27.80 and 22.83 respectively.Afer the experiment the department of pharmacy informed that drug A is Shahaosan and drug b is Yunnan white drug.CONCLUSTON:Compiments of dry socket induced by extracting of lower jaw impacted teeth can be prevented by locally administered with Shahaosan,but no significant effect of alleviating the symptom of dental extraction.
  • The causes of thyreoprival hoarseness and rehabilitation 免费阅读 下载全文
  • The thyroid gland locates at a very complex anatomic region,which controls many important physiological functions and special senses.complications will be resulted from carelessness in operation.Hoarseness caused by injury of recurrent nerve is a common and severe one.OBJECTIVE:To study the causes of thyreoprival hoarseness and rehabilitation.
  • Construction of adenoviral vector for luciferase driven by hTERT core promoter modified with MYC-responsive elements 免费阅读 下载全文
  • AIM:To constuct adenoviral vectors for luciferase driven by human telomerase reverse transcriptase(hTERT) core promoter with multimer of MYC-responsive elements.METHODS:Multimer of MYC-responsive elements was cloned inte the upstream site of hTERT core promoter and the modified hTERT promoter and luciferase were cloned into the plasmid pDC316 to construct shuttle plasmids which cotransfected HEK 293 cells with rescuephasmid pBHGlox(delta)E1,3Cre to achieve recombinant adenoviral vectors.The cytopathic effects and PCR using primers specific for luciferase were used to identify the recombinant adenoviral vectors.RESULTS:Adenoviral vectors with luciferase driven by hTERT core promoter with none or positive and negative six copies of MYC-responsive elements were constructed and amplified.The titer of the adenovirus were 3.5×10^6 pfu/ml,2.5×10^6pfu/ml and 1.5×10^6 pfu/ml respectively determined by plaque assay.CONCLUSION:The further research on transciriptional targeting in osteosarcoma gene therapy can be done using adenoviral vectors with luciferase driven by hTERT promoter with MYC-responsive elements.
  • 物理医学与数字化虚拟人体的实践前景 免费阅读 下载全文
  • 在现代科技前沿领域中,生命科学与信息科学相互交叉的地带生长了数字化虚拟人体新的研究方向。在医学与物理学、数学、计算机科学的交叉领域,“数字化虚拟人体”是物理医学与计算医学的新事物之一。依据人体精细的切片二维图像,通过信息技术,可以建立数字化人体数据库,构成虚拟人体的框架。在这种数据库框架上,赋予物理医学研究成果的参数,可以表达虚拟人体的物理学性能,深化物理学的研究内容。介绍国际上数字化虚拟人体的发展概况及其在物理医学上的应用前景,介绍我国在174次香山科学会议后,国内这一领域的研究进展情况。
  • 心脏康复研究的最新进展 免费阅读 下载全文
  • 心脏康复医学是一门发展中的科学,它的理论与实践处于起步阶段,为适应心血管医学发展的需求,要掌握心脏临床医学的发展动向,并突出本学科特点的优势,发展成为心血管医学中重要的组成部分。心脏康复的研究有着广阔的应用前景,其研究成果将丰富康复医客心血管临床医学。
  • 组织化卒中医疗的概念及国内外特征 免费阅读 下载全文
  • 组织化卒中医疗是指多学科的、合作的和整合的医疗计划,目的是提供给患者最佳医疗服务。最佳医疗服务包括高质量、标准化、有效的和花费效果合适的措施。组织化卒中医疗的基本文件是卒中指南和整合医疗路径。组织化卒中医疗的项目和形式包括欧洲的卒中单元、美国的卒中中心,加拿大阶梯工程和北京组织化卒中医疗体系。
  • 循证医学在康复临床中的应用 免费阅读 下载全文
  • 在康复医学领域如何开展循证医学?循证医学证据的分级,实践循证医学的步骤,以及怎样才能够通过临床医师参与和利用Cochrane协作网、阅读和应用循证医学文献来寻找到目前最好的证据,以解决患者的实际问题;循证医学应用于心肺疾患、神经系统疾患、骨关节疾患等已取得较好的经济效益和社会效益;而目前的部分系统评价所收集的原始文献尚不充分,大部分缺乏大型、多中心随机对照试验的支持,有的系统评价无法得出对临床有帮助的结论。文章综述了康复科主要相关疾病的循证医学研究概况,为临床康复医师如何实践循证医学和进行康复医学科研提供参考。
  • 刘海若重症复合性损伤的康复问题 免费阅读 下载全文
  • 按刘海若康复医疗小组制订的康复医疗计划进行的康复医疗活动,基本达到了预期的目的,可以预料刘海若的功能恢复将是比较理想的。从这个重症复合性损伤的个案治疗中体会到;在综合医院中,康复医疗的早期介入、与临床相关学科的密切配合、强调预防性康复和主动性康复、对多种损伤的全面康复考虑和对康复医疗功能后果的全面考虑等,是制订康复计划和实施康复医疗成功的前提条件。因此,作为综合医院临床科室的康复医学科的医生,必须具有扎实的临床基础。
  • 糖尿病患者的康复治疗与评定 免费阅读 下载全文
  • 目的:观察综合康复治疗对社区2型糖尿病患者的疗效,探讨适合我国国情的社区糖尿病康复治疗模式。方法:对本市社区的2型糖尿病患者进行1年的综合康复治疗随访观察。结果:1年康复治疗后糖尿病患者的空腹血糖较1年前有显著降低,平均降低1.75mmol/L;三酰甘油和胆固醇水平降低明显,高密度胆固醇(HDL-ch)虽有所升高,但差别不显著;体重指数(BMI)、腰臀比(WHR)和血压康复治疗后都有显著下降。糖尿病患者每人每季度平均医疗费用较康复治疗前减少331元,费用下降幅度达41.2%。结论:在社区开展糖尿病患者的康复治疗可有效控制糖尿病患者血糖水平,降低糖尿病危险因素水平,增强患者的体质,这对预防糖尿病并发症的发生起到重要作用。
  • 教育、职业与痴呆流行性的关系 免费阅读 下载全文
  • 背景:在意大利关于痴呆流行病学的信息还是十分有限的,虽然这种认知痢疾已引起强烈的公众的关注。对象及方法:本研究对意大利北部Conselice市Emilia Romagna地区的1016例老年人进行痴呆流行病学及痴呆亚型的流行病学研究评估,患者年龄65-97岁。痴呆与可变的危险因素(教育、职业)相结合也进行评估。结果:痴呆的总体流行率为5.9%(95%的可信区间为4.3-7.8),并随着年龄的增加以幂的形式增加,而且在女性中更高。在痴呆的病例中,50%为Alzheimer‘s病患者,血管性痴呆的发病率为45%。对性别及年龄调整后,是教育而不是职业与AD及VD相关。这种关系不能用职业、生活习惯及高血压或心血管疾病病史来解释。
  • 血管性痴呆患者的行为问题作为功能能力的预测指标 免费阅读 下载全文
  • 对29例血管性痴呆患者治疗前行为问题与痴呆的严重程度与日常生活活动能力(ADL)的关系进行检测。采用一系列逐步回归分析的方法评估痴呆的严重程度、淡漠、去抑郁对ADL的执行功能的影响(总体的、基本的及工具性)。对于总体ADL的影响,淡漠占36%,痴呆严重程度占15%。对于基本ADL的影响,淡漠占27%。痴呆严重程度、执行功能及去抑郁与基本ADL无明显的相关性。对于工具性ADL的影响,痴呆严重程度占37%,淡漠占14%。这些发现突出淡漠除了与总体认知能力相关之外与功能独立性独立相关。
  • 血管性痴呆患者MRI皮层下高密度和脑容积与认知功能的关系 免费阅读 下载全文
  • 目的:对比MRI(皮层下高密度,全脑体积)发现为血管性痴呆认知功能障碍的关系。方法:24例患者均符合NINDS-AIREN血管性痴呆诊断标准(MMSE=19.9±4.2),对其进行综合神经心理评定及MRI脑显像检查。结果:皮层下高密度与精神运动行为明显相关,但与其它的认知行为或整体的认知功能水平无关。相反,全脑容积与整体的认知功能及多数认知行为(包括记忆、语言、视觉统合)明显相关,但与精神运动功能无关。皮层下的高密度不能作为血管性痴呆患者整体痴呆的证据也不能解释多数认知方面的障碍。结论:深度皮层下白质疾病可能是血管性痴呆患者整体认知功能障碍惟一的间接证据。而全脑体积与痴呆明显的相关性对于血管性痴呆的脑机制提出了更多的问题。
  • 白质损伤、定量磁共振成像及痴呆 免费阅读 下载全文
  • 对象:为犹他州Cache县老年人群,可能或很可能发生阿尔茨海默病(AD)的患者85例,血管性痴呆(VD)21例,伴有轻度或中度认知障碍30例,非痴呆但诊断为某种形式神经精神疾病(混合的神经精神疾病组)的患者39例。对照组为20例65岁以上的正常人,排除年龄、性别及病程的因素。方法:对所有患者进行定量及定性磁共振显像分析,并对其进行简单精神状态检查法(MMSE)评分及载脂蛋白E ε4等位基因表现的检测。神经显像检测包括白质、灰质及海马的体积,室脑比率(VBR),并对脑室周围及半孵圆中心区白质的损伤进行定性评定。结果:AD及VD痴呆患者白质损伤与对照组不同,但只有VD患者不同于轻中度认知障碍患者,两痴呆组均表现为明显的脑萎缩。白南损伤随着年龄及痴呆严重程度的增加而增加,脑室周围的白质损伤明显,但只有白质体积的丢失与MMSE评分增多有一定的相关性。脑结构的定量评定与MMSE评分也有一定的相关性。然而,当采用室脑比率检测脑萎缩的程度时,白质损伤对MMSE评分的影响没有意义,惟一有意义的关系是海马体积与MMSE评分。ε4等位基因的表现及MMSE评分没有显著的定位及定量的相关性。结论:白质损伤在老年及痴呆患者中的影响有待讨论。
  • 早期炎症与痴呆的关系 免费阅读 下载全文
  • 背景:炎症反应与心血管疾病密切相关,并且可能与痴呆性疾病相关。本研究对痴呆与炎症的非特异性标志--高敏感性C反应蛋白的长期相关性进行评估。方法:数据来源于檀香山心脏中心,为1968-1970间再次就诊的日本籍美国男性患者,25年后即1991-1996年期间在檀香山亚洲老年人研究中心检查痴呆发生情况。在第二次检查中随机抽取1050例檀香山亚洲老年人中心患者及非患者,对其血浆中的高敏感性C反应蛋白浓度进行检测,按照国际标准,采用神经图像技术及神经心理学检测方法,对痴呆情况进行评估。结果:与最低的四分位数高敏感性C反应蛋白的男性患者相比,超过3个四分位数的男性对于各种类型的痴呆均增加3倍的危险。血管性痴呆发生的危险随着四分位数的增加而增加。这些关系与心血管危险因素及疾病无关。结论:炎症标志物不仅反应周围疾病,而且反应与痴呆有关的脑疾病的机制,并且这个过程在临床症状出现前是可以长期检测到的。
  • 痴呆患者死亡的预测指标 免费阅读 下载全文
  • 目的:对Alzheimer病(AD)患者及血管性痴呆(VD)患者进行为期7年的随访研究,以确定影响死亡率的因素。对象与方法:共145例AD及VD患者,男56例,女89例,随访之初年龄分别为(77±7.9)岁和(80±8.5)岁,采用Cox回归模型对其人口统计学参数、临床变量及生存的关系进行分析。结果:分析显示年龄增加、男性、整体功能水平及摔倒或骨折史与死亡率升高有明显的相关性。VD患者比AD患者死亡率更高,对年龄及性别进行调整后,摔倒或骨折的死亡危险率为1.7%(95%的可信区间为1.12.6)。对64例可获得ApoE基因分型数据的患者采用同样的分析可获得相同的效果,摔倒后的骨折预示着更高的死亡率。另外,ApoE4阳性的患者比阴性的患者有更低的死亡率(P<0.01)。结论:从事对AD患者护理工作的人员应当意识到摔倒/骨折是死亡率的一个预测指标。
  • 采用视觉联合检测Alzheimer型早期痴呆 免费阅读 下载全文
  • 背景:视觉联合检测(VAT)是基于意向记忆术的一种简单的学习任务。检测资料包括6组成对相互作用的物体或动物的绘图,例如一只猴子手中拿着一把雨伞。被测者说出每个物体的名称,然后擦除一个相互作用的物体,令其对另一物体命名。目的:第1个目的是检测VAT方法是否促进学习;第2个目的是研究这种检验方法作为鉴别早期Alzheimer型痴呆的有效性。方法:研究1:对两组老年患者采用视觉联合检测。对A组83例患者采用相互作用的形式,例如:一个猴子拿着一把伞;对于B组79例患者采用并列的方法,例如一个单独的猴子的图片的一个单独的伞的图片。B组接受学习指导,但A组不进行指导。研究2:从随访人群中选择3组患者,Alzheimer型痴呆患者24例,认知能力下降但没有诊断为痴呆的患者21例,肯定没有痴呆的患者204例。无痴呆组的基线检测与Alzheimer型痴呆患者诊断时进行对比,Alzheimer型痴呆患者诊断前1年及非痴呆性减退患者的基线水平进行比较。研究3:为可疑痴呆患者采用神经心理学评定,要用公认的各种痴呆综合征的诊断标准进行诊断。结果:研究1:A组患者的记忆是B组的2倍,因此交互显示,即便是在缺乏指导的情况下也能促进学习。研究2:在97.5%特异性的水平,视觉联合检测对Alzheimer型痴呆在初诊时的敏感性为87.5%,诊断前1年的敏感性为66.7%。认知下降组基线时视觉检测评分比非痴呆组明显低。视觉联合检测比MMSE及CAMCOG的6项图片学习任务用于鉴别诊断更有效。研究3:Alzheimer型痴呆患者VAT评分比血管性痴呆(37例)、前颞叶痴呆(9例)或皮层下痴呆患者(15例)明显降低,但不比Lewy小体痴呆患者(7例)低。各组平均MMSE评分没有明显差异。VAT检测用于DAT与其它类型的痴呆进行鉴别比枯燥乏味的回忆检测更有效。敏感性为79%,特异性为69%。结论:VAT检测对多数的DAT患者诊断前1年有高度的特异性,VAT评分降低在非Alzheimer型痴呆患者中相对不常见。
  • 痴呆患者抑郁综合征及脑综合征的关系 免费阅读 下载全文
  • 目的:阐明痴呆患者抑郁综合征及局部脑综合征可能的关系。方法:对170例连续入院的患者进行研究,其中Alzheimer‘s病患者103例,血管性痴呆患者48例,前颞叶痴呆19例。对所有患者进行神经心理学的检测,包括对抑郁及局部脑综合征的评估。抑郁综合征的评估包括抑郁情绪和焦虑。采用统计学的方法对抑郁情绪和/或焦虑进行进一步的评估。局部脑综合征分析的原则是连续可观察到的症状变量累集,采用逐步对比分析方法,包括前额、皮层下、室壁的和球面散在的个可能的局部脑综合征。对抑郁情绪采用卡方统计方法,对焦虑采用逻辑回归分析的方法(混杂因素包括:年龄、痴呆程度、病程)分析局部脑综合征和抑郁综合征可能的关系。结果:皮层下综合征与抑郁情绪相关(卡方检验,P=0.002;logixtic回归,P=0.002)。室壁综合征与抑郁情绪呈负相关(P=0.010,P=0.013)。在局部脑综合征与抑郁综合征间没有其它的相关性。结论:临床确定为皮层下功能障碍的痴呆患者更易患抑郁综合征。研究结果也提示痴呆患者后脑的功能障碍与抑郁综合征不相关。
  • 老年高血压与Alzheimer病、血管性痴呆和认识功能的关系 免费阅读 下载全文
  • 背景:45-50岁时患高血压可能容易发生Alzheimer病(AD)。但对于65岁以后的高血压是否也有发生Alzheimer病的危险还不能确定,其对认知功能的影响也不能充分的理解。方法:数据来自于一项为期7年的纵向研究,对象为1259例参加医疗保险的非痴呆患者。采用比例风险模型分析高血压与AD及血管性痴呆(VD)发生的关系。采用统一的评估方程对比有和没有高血压患者在评估中记忆、语言和视野空间/认知功能的情况。结果:1259例患者中,731例(58.1%)有高血压病史,并伴有糖尿病、脑卒中和心脏病。高血压病史与AD发病危险性增加无关(RR=0.9,95%可信区为0.7-1.3),但与VD发生的危险性相关(RR=1.8,95%可信区间为1.0-3.2)。实验中正常个体高血压与记忆、语言及总体认知功能的改变无关,那些单独有高血压或心脏疾病不均加VD发生的危险,然而,两者同时存在时,VD的发生可增加3倍。高血压与糖尿病同时存在时VD发生的危险性增加6倍。结论:65岁以后的高血压与AD的发生不相关,对记忆、语言或总体认知功能没有负面的影响。高血压病史可能是VD的前奏,尤其对于伴有心脏疾病或糖尿病患者。
  • 糖尿病与痴呆、Alzheimer病及血管性认知障碍的关系 免费阅读 下载全文
  • 背景:糖尿病是否为Alzheimer‘s病发病的危险因素报道不一,在一项5年的纵向研究中,我们分析了糖尿病与痴呆发生的关系,包括Alzheimer‘s病及血管性认知障碍。方法:本研究为加拿大健康及老年人研究中的一项次要研究,是对有代表性的老年痴呆人群的研究。结果:对5574例研究之初没有认知障碍的患者进行5年的随访。基线状态的糖尿病患者与血管性痴呆(RR=1.62;95%可信区间为1.12-2.33)及其亚型有相关性,包括血管性痴呆(RR=2.03;95%可信区间1.15-3.57)及不伴有痴呆的血管性认知功能障碍(RR=1.68;95%可信区间为1.01-2.78)。糖尿病与AD和VD混合型痴呆(RR=1.30;95%轲信区间为0.90-1.76)、Alzheimer‘s病(RR=1.30;95%可信区间为0.83-2.03)及全部痴呆(RR=1.26;95%可信区间为0.90-1.76)不相关。结论:尽管对于Alzheimer‘s病中血管因素的作用得到重视,而且糖尿病与血管性认知障碍相关,但本研究中我们没有发现糖尿病与Alzheimer‘s病有相关性。
  • 加兰他敏治疗阿尔茨海默(Alzheimer)病 免费阅读 下载全文
  • 背景:加兰他敏最初从几种植物中提取出来,包括黄水仙。但现在多为合成制剂。加兰他敏是一种特定的、竞争性的、可逆的乙酰胆碱酯酶抑制剂。它也是烟碱酸胆碱能受体位置异构调节剂。使胆碱能的烟碱的神经传递成为可能。少量的早期研究表明,对阿尔茨海默(Alzheimer)病患者轻度认知障碍及整体是有益的,最近已出版的几项多中心临床研究也发现了阳性的结果。加兰他敏的应用在29个国家已得到正式的批准。目的:本研究的目的是评估加兰他敏对可能的AD患者的临床效果,并研究可能的调节机制。主要结果:7项研究符合入选标准,其中6项为2期和3期基金资助多中心研究。2项为12周,1项为13周,1项为5个月,1项为29周,26项为6个月。5个月或更长时间的研究集中起来按6个月进行分析,以每天16-32mg的剂量治疗3-6个月,加兰他敏有明显的治疗效果。结论:本项研究中的患者与那些早期抗痴呆治疗的AD患者相似,即主要为轻度到中度的损害的患者,加兰他敏对严重损害的患者的作用还没有评定。然而,本项研究显示在3,5,6个月的治疗期中,加兰他敏均显示一致的阳性效果。另外,虽然不同剂量的效果没有统计学差异,但8mg/d以上的剂量大部分有一致统计学意义。因此,有证据表明加兰他敏对整体评估、认知检测、日常生活活动能力及行为评定的效果。加兰他敏对认知功能的作用程度与其它的乙酰胆碱酯酶抑制剂的效果是一样的。加兰他敏的安全范围与其它乙酰胆碱酯酶抑制剂相似,即胆碱介导的胃肠道症状。在5%的时程内,没有副作用发生。在一项研究中,对药物进行为期4周的滴定,结果显示16mg/d是最耐的耐受剂量。由于这个剂量与更高的剂量在效果上没有统计学的差异,所以该剂量是一种较适宜的开始剂量。加兰他敏的长期使用还没有可控制的评估。
  • 吡拉西坦对痴呆及认知障碍的效果 免费阅读 下载全文
  • 背景:吡拉西坦是一种可能提高记忆及其它智力功能的药物,但其机制还不完全清楚,而且还有争议。低剂量的吡拉西坦可能通过增加ATP路径中氧及葡萄糖的利用而发挥作用,高剂量的作用机制则与血小板抗集簇性作用和血液流变学的抗血栓作用相关(Moriau 1993)。通过促进红细胞的变形性及减少受损红细胞粘连到上皮细胞改善中心及周围微循环。吡拉西垃对于阿尔茨海默(Alzheimer)病、血管性痴呆及非特异性痴呆的效果仍有争议,尤其是小的临床研究,较大规模的临床研究结果更趋肯定其效果。不管是未分类还是根据痴呆的主要亚型来分类(血管性痴呆、Alzheimer病或血管性与Alzheimer病混合性)吡拉西拉对痴呆的效果不一致,但吡拉西拉在几个欧洲国家是改善认知障碍的常用药物。目的:确定吡拉西拉对认知障碍及各种痴呆特征的临床效果,包括痴呆的主要亚型:血管性痴呆、Alzheimer病或混合性痴呆,或未分类的痴呆或没有达到痴呆诊断标准的认知障碍。结果:不幸的是许多横断面研究和第一阶段的数据是不可利用,或不能选取。整体效果的改变是所提取数据显示的惟一有意义的结果。个体研究有不同质的证据,卡方值为20.8(df=5).采用一个固定的效果模型,与对照组比较吡拉西坦组改善的比值比为3.55(95%的可信区间为2.45-5.61);如果采用随机效果模型,比值比为3.47(范围为1.29-9.30)。如果排出一个单盲研究,固定效果模型比值比达到3.36(范围为2.29-4.99),如果采用随机效果模型则比值比为2.89(1.01-8.24)。吡拉西坦对认知及其他方面的效果还不肯定。结论:从已出版的文献获得的证据不支持对痴呆及认知障碍患者使用吡拉西坦。虽然有证据表明其对整体印象的改变是有作用的,但对任何其它特异的特征没有好处。需要通过如下方法对吡拉西坦的作用进行进一步的评估:(1)从已发表的研究获得个别患者的数据的评论;(2)对采用目前的诊断标准确诊的患者采用吡拉西坦进行一项随机研究。研究应持续至少6个月的时间。采用对改变敏感的特定的认知量表进行评定,如临床整体印象改变、独立水平,护理者生活质量量表也应在此研究中一起使用。
  • 卵磷脂治疗痴呆及认知障碍 免费阅读 下载全文
  • 背景:研究证明阿尔茨海默病(Alzheimer)病患者脑内缺乏将胆碱转换成乙酰胆碱的酶。卵磷脂是主要的食物来源的胆碱,所以过多的消耗可能减少痴呆的进展。目的:确定卵磷脂在治疗痴呆或认知障碍中的作用。结果:共纳入12随机对照研究,包括265例Alzheimer病患者,21例帕金森痴呆患者,90例有主观记忆问题患者。没有一项试验报告卵磷脂对Alzheimer病及帕金森痴呆有明确的临床效果。几乎没有实验可用于meta分析。惟一有统计学差异结果为对照组的副作用,且只有一项试验,考虑可能为假的结果。一个戏剧性支持卵磷脂的效果是在一项中对患者的主观记忆问题有益。结论:随机对照研究并不支持对痴呆患者采用卵磷脂进行治疗。适当的效果不能排除,但到目前为止,小研究的结果并不代表随机对照试验的观点。
  • statins预防阿尔茨海默(Alzheimer)病 免费阅读 下载全文
  • 背景:最近有两项研究表明,statins治疗可减少70%的阿尔茨海默(Alzheimer)病的发生。一项研究为2000年Wolozin在3个医院进行的有代表性的研究,另一项为英国2000年Jick对全科医生收治的可行走患者进行的一组病例对照研究。由于两项研究均不是随机试验,所以statins治疗与Alzheimer病发生减少很可能是研究中没有统计的其它原因的作用。然而,扩展的生物学及人口统计学数据使statins治疗延迟及预防Alzheimer病的发病及临床表现似乎是可以接受的。目的:这项回顾性研究的目的是发现可能支持或反对statins治疗效果这一假设的临床证据。结果:没有发现随机试验。但有一项重要的临床试验的论文将在2002年晚些时间要发表。结论:没有好的证据支持statins治疗减少Alzheimer病的发生。然而,非随机临床研究的生物学及人口统计学证据表明,血浆胆固醇降低可能延迟Alzheimer病的发生。临床研究的统计分析结果显示在将来的Alzheimer病研究中statins治疗有很高的优势。
  • 维生素E治疗阿尔茨海默(Alzheimer)病 免费阅读 下载全文
  • 背景:维生素E可在饮食中获得,其作用为抗氧化,清除有毒的自由基,自由基可能参与阿尔茨海默(Alzheimer)病的病理过程,这导致维生素Alzheimer病可能是有意义的。主要结果:只有一项研究符合入组标准,研究中341例患者主要结果生存时间是4个终点的第1位,4个终点为死亡、收容入院、基本生活活动能力丧失2/3或严重痴呆(为整体临床痴呆3级)。这项调查报告两年的时间内到达主要终点每组患者的数量。与58例完成研究者相比,到达终点的患者为45例,这看起来维生素E有一定的益处。Peto比值比为0.49,95%的可信区间为0.25-0.96。然而,服用维生素E的患者发生摔倒的数量更多,分别为12和4例,比值比为3.07,95%的可信区间为1.09-8.62。对于特定的终点或对于认知、依赖性、行为紊乱及日常生活活动能力去解释这种报告结果是不可能的。结论:维生素E治疗Alzheimer病的有效性证据还不十分充分。已出版研究可接受的方法学限定在中等疾病患者,研究结果也很难去解释。对于可能的益处有充分的证据进行进一步的研究,对于服用维生素E组的患者比对照组有更多的摔倒需要进一步的评估。
  • 阿司匹林治疗血管性痴呆 免费阅读 下载全文
  • 背景:阿司匹林被广泛用于诊断为血管性痴呆的患者,在一项研究中,英国老年精神科医生对80%有血管危险因素认知障碍患者被给予阿司匹林。然而,大量的问题没有答案。阿司匹林治疗血管性痴呆有令人信服的效果吗?阿司匹林能改善认知功能或改善预后吗?另外,其引起的脑出血或胃出血比其效果更重要吗?目的:评估使用阿司匹林治疗血管性痴呆有效性的证据。主要结果:没有符合标准的研究入选。结论:最近的一项相关研究是2002年1月进行的,再没有新的研究。仍没有证据表明阿司匹林对血管性痴呆治疗是有效的,进一步的研究需要评估阿司匹林对认知功能及其它结果如行为和生存质量的影响。
  • 定位力检测对痴呆患者认知及行为能力的影响 免费阅读 下载全文
  • 背景:定位力检测是改善老年认知能力下降患者生存质量的首要技术,这种检查是对患者进行时间、地点、人的辨认,这些信息可能促进患者对周围环境有更多的理解,并可能导致自控能力及自尊心的改善。但在痴呆患者的心理治疗服务这种方法还没有一致的意见,所以为确定这种治疗的效果对已有证据进行系统的综述是很有必要的。结果:对6项随机对照研究进行分析,总共125例患者入组,试验组67例,对照组58例,结果被分为认知及行为两个亚组,认知及行为的效果显示支持这项治疗。结论:有证据支持定位能力的改善对痴呆患者的认知及行为是有益的。进一步的研究可以判定定位能力检测的特殊效果。治疗后期定位能力有多大益片还不太清楚,但若要保持可能的益处需要连续的治疗。
  • 消炎痛治疗阿尔茨海默(Alzheimer)病 免费阅读 下载全文
  • 背景:阿尔茨海默(Alzheimer)病的发病机制包括细胞因子前列腺素、自由基和神经胶质细胞在内的炎症过程。非甾体类的抗炎药物,如消炎痛可减少炎症反应,因此,这些药物在治疗Alzheimer病中可能有一定作用。目的:检测消炎痛在治疗Alzheimer病患者中的效果。主要结果:只有一项研究入选。采用个体认知检测、MMSE、Alzheimer病评估量表、Boston命名检测、Token检测评定消炎痛治疗组与对照组没有统计学差异。漏码及死亡率是可用于评估的惟一报告结果。消炎痛组漏码率比对照组高,分别为10/24和6/20。治疗组的胃肠反应更普遍,治疗组与对照组分别为5/24和1/20。两组的死亡率没有统计学的差异(P=0.9)。结论:在这项试验及其后作者对数据分析的结果基础上,消炎痛不能被推荐用于轻度到中重度Alzheimer‘s病的治疗。剂量为100-150mg/d时,严重的副作用将限制其使用。
  • 高血压和高胆固醇血症是引起老年痴呆病的两大危险因素 免费阅读 下载全文
  • 早老性痴呆症早期诊断新法 免费阅读 下载全文
  • 预测阿尔茨海默病发病有新法 免费阅读 下载全文
  • 老年性痴呆的国际疾病诊断标准 免费阅读 下载全文
  • 痴呆病人出现精神症状时药物的选择 免费阅读 下载全文
  • 帕金森病与滥用药物有关 免费阅读 下载全文
  • 雌激素可防止或延缓早老性痴呆 免费阅读 下载全文
  • 老年人步态异常有助于预测非阿尔茨海默病(Alzheimer)性痴呆症的发生 免费阅读 下载全文
  • 老年痴呆新基因位点发现 免费阅读 下载全文
  • 中医防治脑衰老的新理论 免费阅读 下载全文
  • 痴呆症又有新说法 免费阅读 下载全文
  • 老年人中度高血压对认知功能有益 免费阅读 下载全文
  • 使用抗炎药物可减少患阿尔海默氏病的危险 免费阅读 下载全文
  • 阿尔茨海默病的保护因素——运动和户外活动 免费阅读 下载全文
  • 探讨运动对阿尔茨海默病(Alzheimer‘s disease,AD)是否同样具有保护作用以及有什么样的特点。方法:采用配对的病例对照研究方法。观察组和对照组各127例。病例来源于痴呆流行病学调查中的确诊病例。结果:个人生活习惯方面,从15岁到调查时,观察组年龄段未曾有散步、跑步和打拳习惯者,患AD的危险性增加,各年龄段的各种活动频率中每周活动1-2次或每月活动1次的患病的危险性高于每天活动者。15-24岁这个年龄段每天活动<1h的OR值>每天活动>2h者。从25-49岁表现为每天活动<0.5h者的OR值>每天活动>2h值,50岁以上则为从不活动者的OR值>每天活动>2h的人。结论:从年轻时就开始多运动,可能是预防认知功能下降的一个好办法。
  • 单光子计算机断层扫描对单侧脑梗死早期持续康复治疗后脑功能活动状态研究 免费阅读 下载全文
  • 目的:探讨脑梗死后早期神经康复治疗对脑单光子计算机断层扫描(SPECT)局部脑血流(rCBF)的影响。方法:比较8例急性单侧脑梗死患者经早期神经康复持续治疗后&99mTc-双光胱乙酯SPECT rCBF兴趣区法测定结果,并与患者临床神经功能的转归和磁共振改变相对照。结果:病侧额区、上额区以及健侧额区局部脑血流明显增加,与临床神经功能的转归相一致。结论:脑梗死后早期神经康复治疗可以促使脑功能改善,同时显示脑SPECT显像在动态研究脑功能变化中有一定价值。
  • 高血压患者心理卫生状态与生活满意度的关系 免费阅读 下载全文
  • 目的:探讨高血压患者生活满意度和精神卫生状况间的关系。方法:以生活满意度调查表和SCL-90为测量工具,对68例高血压患者进行对照研究和直线相关分析。结果:高血压患者生活满意度平均得分23.4,处于中等偏下水平,除居住和子女孝顺外与正常对照均有显著性差异(P<0.01)。直线相关分析提示生活满意度低导致患者抑郁、焦虑、人际敏感和躯体化症状多。结论:高血压的发病与心理应激和生活满意度有关,家庭和睦、社会保障体系健全、良好的人际关系和经济状况,是减少应激和提高患者精神卫生状况的重要环节。
  • 超声乳化白内障吸除术后和囊外白内障摘除术后视功能比较 免费阅读 下载全文
  • 目的:本组资料比较白内障超声乳化吸除联合人工晶状体植入术(PHACO+IOL)和囊外摘除联合人工晶状体植入术(ECCE+IOL)和2种手术后患者视功以的变化。方法:作PHACO+IOL的患者98例,和作ECCE+IOL的患者77例,分别在手术前,手术后1周、1个月和3个月作眼科检查并完成视功能问卷。结果:在手术后1周,超声乳化组视功能得分及各指标得分均高于囊外摘除组(P<0.05);在术后1个月和3个月,超声乳化组视功能得分以及感觉适应和立体觉2个指标的得分高于囊外摘除组(P<0.05),对日常活动的限制和周边视野2个指标的得分2组差异无显著性意义(P>0.05)。结论:PHACO+IOL比ECCE+IOL有较大的视功能改善,特别是在感觉适应和立体觉方面,在对日常活动的限制和周边视野的改善方面,2种手术方式之间差异无显著性意义。
  • 运动康复促进脑梗死大鼠学习记忆功能恢复的研究 免费阅读 下载全文
  • 目的:研究运动康复对脑梗死大鼠学习记忆功能的影响,为运动训练改善脑梗死患者学习记忆提供理论依据。方法:wister大脑中动脉缺血梗死雄性大鼠模型,随机分为康复训练组、模型组和自由活动组。康复组于术后第4d给予平衡、抓握、行走及水迷宫训练、模型组于普通笼内饲养;自由组可在康复训练器材上自由爬行但不给予强制训练。检测4周后3组大鼠在Y-迷宫和一次性被动回避反应中的学习和记忆能力。结果:康复组在Y-迷宫分辨学习能力和一次性被动回避反应记忆能力的检测均优于模型组和自由组(P<0.05)。结论:康复训练可促进脑梗死大鼠学习记忆能力的恢复。
  • 垂体腺苷环化酶激活肽对缺血再灌注脑神经元凋亡的作用 免费阅读 下载全文
  • 目的:观察垂体腺苷环化酶激活肽(pituitary adenylate cyclase-activating polypeptide,PACAP)对缺血再灌注脑神经元凋亡的防治作用。方法:利用四血管结扎法,建立老龄大鼠脑缺血再灌注模型,侧脑室注射PACAP,观察脑组织丙二醛(MDA)含量和超氧化物歧物酶(SOD)、谷胱甘肽过氧化物酶(GSH-Px)活性,计数海马CA1区存活和凋亡神经元数目,电镜观察神经元的超微结构变化。结果:PACAP治疗后脑组织MDA含量为(1.35±0.39)nmol/mg,SOD和GSH-Px活性分别为(115±20)NU/mg、(10.3±2.0)U/mg,与缺血再灌注组有明显差异(P<0.05),海马CA1区存活和凋亡神经元数目为48.8±4.3,14.3±2.9,能促进神经元存活和减轻凋亡损伤(P<0.01),保护超微结构。结论:PACAP的保护作用可能与其降低脑组织氧自由基水平,提高抗氧化酶活性,防止神经元凋亡有关。
  • 雌二醇对拟痴呆小鼠学习记忆功能的影响 免费阅读 下载全文
  • 目的:在氯化铝(AlCl3)所致拟痴呆动物模型基础上,探讨雌二醇对拟痴呆小鼠记忆功能保护作用及其作用机制。方法:皮下注射AlCl3 70mg/d共7d,实验组腹腔注射雌二醇0.3,0.6,0.9mg/kg共20d后,用跳台、避暗等实验方法测定小鼠学习记忆能力,同时测定小鼠脑内乙酰胆碱脂酶(AchE)及脑B型单胺氧化酶(MAO-B)的含量。结果:AlCl3所致痴呆小鼠记忆能力明显降低,表现为避暗、跳台实验的错误次数明显增加,以及增加脑MAO-B含量及脑内AchE的含量,雌二醇各剂量组能够减少小鼠电击次数(错误次数),24h重复实验,可延长跳下平台的潜伏期及进入暗箱的潜伏期,错误次数明显减少。同时降低了脑内AchE和MAO-B。结论:雌二醇对A1C13所致痴呆小鼠记忆障碍具有保护作用,能增强学习记忆能力。
  • DCG—Ⅳ在大鼠脑损伤及二次脑损伤中的神经保护作用 免费阅读 下载全文
  • 目的:探讨Ⅱ组mGluRs激动剂DCG-Ⅳ对弥漫性脑损伤(Diffuse Brain Injury,DBI)及其合并二次脑损伤(Secondary Brain Insult,SBI)后损伤脑组织的神经保护作用。方法:单纯DBI及合并SBI后,脑室注射DCG-Ⅳ(100μmol/L,10μl)或生理盐水(10μl),观察大鼠行为、脑组织含水量及皮层损伤神经元数变化。结果:DCG-Ⅳ对DBI后大鼠死亡率(生理盐水组死亡10只,DCG-Ⅳ组死亡9只;P>0.05)、皮层损伤神经元数量及脑组织含水量无明显影响(P>0.05);但可降低合并SBI组大鼠死亡率(生理盐水组死亡20只,DCG-Ⅳ组死亡11只;P<0.05)、减轻合并SBI后的脑水肿程度,减少神经元损伤数量(P<0.05)。结论:DCG-Ⅳ对DBI合并SBI后损伤脑组织有一定的保护作用。
  • 2型糖尿病患者血清瘦素水平的分析 免费阅读 下载全文
  • 目的:通过2型糖尿病患者与正常对照者之间的比较,分析血清瘦素与多种影响因素的关系。方法:对样本人群进行流行病学问卷调查,体检并测定了血糖、血脂、胰岛素和血清瘦素等生物指标,通过病例对照研究方法加以分析。结果:2型糖尿病患者血清瘦素为(9.43±6.15)ng/ml,正常对照为(9.48±5.60)ng/ml。无论有无糖尿病肥胖者血清瘦素约是非肥胖者的2倍,女性约是男性的3倍。结论:2型糖尿病患者与正常对照组间的血清瘦素不存在显著性差异,可能与患者坚持治疗病情控制良好有关。血清瘦素受到吸烟、性别、体脂、血脂和饮食等多方面因素的共同影响,高密度脂蛋白胆固醇可能是其保护因素。
  • 下颌骨牵张成骨和牵张器拆除时机的评价 免费阅读 下载全文
  • 目的:牵张成骨是治疗颌骨畸形和骨缺损的新方法,但力学研究及由此而确立的牵张器拆除时机的研究甚少。通过建立了山羊下颌骨牵张模型,观察下颌骨牵张后的物理、机械特性,探索牵引器拆除的时间。方法:8只山羊单侧下颌骨2次/d,1mm/d,共8d,后以牵开器继续固定至4周,行放射学、组织学、骨密度及力学测试。结果:牵拉术后下颌骨成骨明显,牵拉后2周,X线示骨间隙内新骨已基本连接骨缺损,4周时骨化明显。其骨密度与正常松质骨无明显差别,极限载荷为正常侧的61%。结论:生长期山羊为一良好的下颌骨牵张模型动物,牵拉后4周可以考虑去除牵开器。
  • 脑血管血液动力学检测在脑血管病防治中的应用价值 免费阅读 下载全文
  • 脑血管血液动力学(cerebral vascular hemodynamic,CVHD)检测是一种主要用于脑血管疾病诊断的无创伤性检测方法。其主要检测指标包括脑血管最大流速(Vmax)、最大流速(Vmin)、平均流速(Vmean)、平均血流量(Qmean)等运动学指标和外周阻力(RV)、特性阻抗(Zcv)、脉搏波波速(WV)、动态阻力(RV)、临界压(CP)、舒张压与临界压差值(DP)等动力学指标。CVHD检测指标能够从不同角度反映脑血管的功能的生理和病理状态,在脑血管疾病的病因研究、早期诊断、卒中高危人群筛选、预防和治疗效果观察以及预后研究中具有重要的应用价值。随着流体力学的研究进展和CVHD检测临床应用研究的深入,CVHD在脑血管病防治中发挥更为重要的作用。
  • 脑卒中的基因治疗 免费阅读 下载全文
  • 脑卒中后,在其周边带存在一可逆的半暗带部分,在半暗带区注入外源性基因或改变神经元的基因表达,可保护半暗带,阻止脑卒中后缺血性损伤的发生、发展。近年来,随着分子生物学技术的进步,新的基因不断发现。对药物治疗无效不能外科手术的患者而言,基因治疗脑卒中是一种希望和新的可探索的治疗方法。文章对脑卒中的基因治疗的原理、实验方法、治疗意义进行综述。
  • 帕金森病患者的健康相关生活质量及其影响因素 免费阅读 下载全文
  • 炎性细胞因子与脑缺血 免费阅读 下载全文
  • 小GTP蛋白Rho家族在神经损伤修复中的作用机制 免费阅读 下载全文
  • 手术、外伤、肿瘤、炎症等原因常造成神经的损伤。如何促进损伤后的修复再生是目前神经康复的重要研究内容。最新的研究显示小GTP蛋白Rho家庭可显著促进肌动蛋白的形成,从而促进神经元的存活并促进其再生。为此,对近几年在小GTP蛋白Rho家族的研究进展进行综述。
  • 脑卒中患者损伤部位与功能预后的关系 免费阅读 下载全文
  • 雌激素及植物雌激素治疗老年性痴呆的研究现状 免费阅读 下载全文
  • 脑血管病吞咽障碍的康复评定 免费阅读 下载全文
  • 吞咽障碍是脑血管病患者常遇到的问题,给患者带来极大痛苦,影响患者的生存质量。如何客观地评定吞咽障碍是文章所介绍的内容,正确地了解吞咽障碍的发生过程、判断其障碍程度、障碍部位,对今后的康复工作有着十分重要的作用。
  • 从循证医学角度谈中医药防治脑卒中的研究 免费阅读 下载全文
  • 腹针对脑卒中患者的康复作用 免费阅读 下载全文
  • 目的:观察腹针对脑卒中的疗效,探讨其原理。方法:脑卒中患者206例腹针治疗者作为观察组,脑卒中194例普通针法治疗者作为对照组。对两组康复疗效做出比较,同时对脑卒中组单一腹针治疗者和腹针加普通针法者再进行疗效比较。结果:病程≥3个月者,腹针组疗效高于普通针组(P<0.01),疗程缩短3-7d;而病程>3个月者,腹针组及腹针加普通针组疗效均高于对照组(P<0.01-0.05);疗程明显缩短(P<0.05)。结论:腹针疗法操作简便,处方规范,无疼痛,显著提高疗效,缩短疗程。
  • 不同类型失语症的康复训练技术 免费阅读 下载全文
  • 脑卒中患者运动疗法治疗前后的肌张力 免费阅读 下载全文
  • 脑卒中早期实施医疗体育训练248例 免费阅读 下载全文
  • 氟西汀治疗血管性抑郁症 免费阅读 下载全文
  • 目的:观察抗抑郁剂氟西汀(百忧解)对血管性抑郁症的治疗效果。方法:68例血管性抑顾症患者,随机分为氟西汀组(n=38)和对照组(n=30)。在治疗前和治疗后第4,8周分别进行汉密尔顿抑郁量表(HAMD)评分。结果:与对照组相比,治疗组HAMD评分减分率较高(P<0.01)。结论:氟西汀治疗可显著改善血管性抑郁症患者的抑郁状态。
  • 脑卒中2例康复治疗体会及效果分析 免费阅读 下载全文
  • 脑梗死偏瘫患者康复与单纯药物治疗160例肢体功能恢复效果比较 免费阅读 下载全文
  • 冬季性抑郁对脑卒中患者Barthel指数的影响 免费阅读 下载全文
  • 急性脑梗死患者患肢肌张力出现时间对功能重建的影响 免费阅读 下载全文
  • 目的:探讨急性脑梗死患者患肢肌张力出现早晚对运动功能重建的影响。方法:按脑梗死后10d内出现或不出现肌张力,将50例急性脑梗死患者分为A,B两组,对两组患者治疗前后神经功能缺损积分和Barthel指数(BI)积分,及出院时行走能力进行比较。结果:A,B两组治疗后神经功能积分和BI积分,以及出院时步行能力有显著性差异。结论:急性脑梗死患者肌张力出现越早,其运动功能恢复越好,但要特别注意肌张力出现后及时应用抗痉挛手法防止痉挛。
  • 固定位训练并用气血循环机对脑卒中肩痛的防治作用 免费阅读 下载全文
  • A型肉毒毒素肌肉注射治疗脑血管病后肢体痉挛36例 免费阅读 下载全文
  • 目的:探讨A型肉毒毒素(BTX-1)肌肉注射治疗脑血管病后肢体痉挛的疗效。方法:对36例血管病后肌痉挛患者用国产BTX-A注射,注射剂量、位点根据受累肌肉大小多少程序个体化用药,观察注射前后肌力肌张力变化分别以康复治疗。结果:治疗后随着注射部位肌肉痉挛程度降低,配合康复治疗对痉挛性肌张力增高患者较前明显改善。结论:BTX-A肌肉注射配合康复治疗对脑血管病后肌痉挛是有较好的治疗效果。
  • 减重踩车训练对脑卒中偏瘫患者步态的影响 免费阅读 下载全文
  • 关于进一步加强残疾人康复工作的意见 免费阅读 下载全文
  • 慢性心力衰竭患者运动耐力改变及运动处方研究现状 免费阅读 下载全文
  • 急性心肌梗死患者心脏康复时应用早期活动5级法的评价 免费阅读 下载全文
  • 急性心肌梗死7例2周康复训练效果分析 免费阅读 下载全文
  • 雾化吸入爱喘乐对慢性阻塞性肺疾病肺功能的影响 免费阅读 下载全文
  • 步行运动对2型糖尿病患者血糖、血脂的影响 免费阅读 下载全文
  • 心脑宁治疗糖尿病合并抑郁症的疗效观察 免费阅读 下载全文
  • 糖尿病患者血清骨钙素和骨矿含量变化的分析 免费阅读 下载全文
  • 运动疗法对妊娠糖尿病的影响 免费阅读 下载全文
  • 目的:探讨运动疗法对妊娠糖尿病血糖的影响。方法:用上肢功率计及家庭运动方案治疗孕期在22-34周的妊娠期血糖异常者51例,观察运动治疗前后血糖变化情况。结果:过3-9周运动疗法治疗。41例坚持上肢功率计运动及家庭运动的孕妇。在没有使用胰岛素的情况下,空腹血糖、餐后1h、餐后2h血糖显著降低。较运动前下降2.0-3.5mmol/L,达到控制范围。总有效率80%。结论:安全有效的运动疗法对部分妊娠糖尿病患者可以免除胰岛素治疗。
  • 女性易抑郁与基因有关 免费阅读 下载全文
  • 原发性骨质疏松症诊断技术的临床应用评价 免费阅读 下载全文
  • 中医通补法治疗原发性骨质疏松症的作用机制研究 免费阅读 下载全文
  • 目的:探讨中医通补法对原发性骨质疏松症的作用机制。方法:观察40例原发性骨质疏松症患者,随机分为治疗组30例,用中药通补强骨汤治疗;对照组10例,用健骨钙加霜叶红治疗。结果:经一个疗程共3个月治疗,疼痛等症状改善方面,治疗组明显优于对照组(P<0.05),并能提高腰椎和股骨骨密度,其中腰椎2-4骨密度变化与对照组相比有显著性差异(P<0.05);中医证候疗效、骨密度疗效明显优于对照组治疗,能升高血清骨钙素水平和女性患者血雌二醇水平。结论:通补强骨方能升高血雌二醇水平,抑制骨吸收,提高血清骨钙素水平,增加成骨细胞活性,从而升高骨密度,改善症状,提示其作用机制与抑制骨吸收,促进骨形成,提高骨密度有关。
  • 中医药防治骨质疏松症研究现状 免费阅读 下载全文
  • 从临床研究和实验研究两方面总结近五年来中医药防治骨质疏松症现状,祖国医学对该症病因病机的阐述、辨证分型、各种治疗方法的应用情况,以及应用现代研究方法对中医药防治骨质疏松症机理的认识。
  • 脑性瘫痪高患病率胎尸脑血管临床解剖学特征 免费阅读 下载全文
  • 目的:观察6-7月龄早产儿脑血管的解剖特征,探讨早产儿脑性瘫痪发病率高的形态学基础。方法:解剖观测6月龄和7月龄死亡1h胎尸脑血管各60例。均剪除颅盖和部分脑膜用水冲去脑浆,保留相应的动脉和静脉结构,用手术显微镜观测之。结果:胎尸6-7月龄脑血管,按血管吻合网的部位,脑动脉可分为大脑皮质动脉网;间脑、基底核动脉网和脑干、小脑动脉网。大脑深部髓质的动脉细小稀少又处于动脉网终支交界处。结论:6-7月龄胎儿大脑深部髓质供血较差,易受缺氧伤害。
  • 高危儿监测与脑性瘫痪的早期诊断 免费阅读 下载全文
  • 病毒性脑炎患儿肌力和语言功能恢复30例报告 免费阅读 下载全文
  • 心理干预和暗示治疗儿童癔症 免费阅读 下载全文
  • 军医大学研究生心理健康与人格特征分析 免费阅读 下载全文
  • 目的:了解军医大学研究生的心理健康状况和人格特征。方法:采用症状自评量表(SCL-90)、艾森克成人个性问卷(EPQ)对264名军医大研究生进行测试,619名本校本科生作为对照组。结果:(1)军医大学研究生存在心理问题者占12.12%,低于军医本科生21.97%的阳性率。除人际关系外,各项因子高于常模(P<0.01),但均低于对照组(P<0.01)。女生组各项分数均低于男生组,表现在强迫、恐怖和精神病性因子有明显差异;(2)阳性者症状主要表现为强迫、人际关系敏感、敌对、抑郁和偏执;(3)与阴性者比较,SCL-90筛查阳性者个性特征表现为N分离、P分高、E分低(P<0.01)。不同性别研究生E分和N分无显著差异。结论:部分军医大研究生有心理问题,其个性特征表现为内倾、不稳定。因此,应加强对军医大研究生这一特殊群体的心理健康教育。
  • 心理精神疾病患者睡眠型态紊乱的心理行为干预 免费阅读 下载全文
  • 城市与农村精神分裂症患者的家庭负担 免费阅读 下载全文
  • 目的:探讨城市与农村精神分裂症患者的家庭负担及其影响因素。方法:用家庭会谈量表(FIS)对家住城市或农村的精神分裂症患者各70例的主要照料者进行评定,以及对患者病情与一般资料进行评定。结果:城市与农村患者照料者的FIS总平分分别是26.03±7.47与25.71±7.54,客观负担以经济负担最明显,其次是娱乐与家庭日常活动的负担,两组无显著性差异。城市患者家庭负担与其病期正性相关,农村患者家庭负担与病情严重程度正性相关。结论:对精神分裂症患者进行早期有效的防治同时,给予这些特殊家庭更多的经济与社会支持是很有必要的。
  • 提高精神病患者家庭社会处境的调查研究 免费阅读 下载全文
  • 精神病患者的生活质量与社会支持的关系 免费阅读 下载全文
  • 目的:了解精神病患者的生活质量与社会支持的关系。方法:用精神病患者生活质量问卷、社会支持评定量表调查250例精神病患者,比较高低生活质量组间社会支持、高低社会支持组间生活质量的差异,生活质量民社会支持间的相关分析。结果:高低生活质量组间的主观支持及社会支持总分的差异有显著性,高低社会支持组间的生活质量的生理、心理、社会及症状各维度差异有显著性,主观支持与生理、心理、社会及生存总分的相关和显著性,支持利用率与心理、社会及生存总分的相关有显著性,支持总分与心理、社会、症状及生存总分的相关有显著性。结论:精神病患者的社会支持对生活质量有明显影响。
  • 工娱疗法辅助利培酮改善精神分裂症阴性症状43例 免费阅读 下载全文
  • 抑郁症患者自评生活满意度和痊愈状况分析 免费阅读 下载全文
  • 儿童精神分裂症特征分析132例2年随访 免费阅读 下载全文
  • 心理康复教育在甲状腺功能亢进患者接受^131I治疗中的作用 免费阅读 下载全文
  • 精神分裂症后抑郁患者支持性心理治疗34例 免费阅读 下载全文
  • 酒精所致精神障碍患者疾病知识的掌握情况 免费阅读 下载全文
  • 认知治疗改善精神分裂症患者认识及部分行为能力的作用 免费阅读 下载全文
  • 目的:观察认识治疗对改善精神分裂症患者认识及部分行为能力。方法:将符合CCMD-2-R精神分裂症诊断标准的患者的68例随机分为A,B两组:分别采用精神药物配合认知治疗和精神药物配合支持性心理治疗。与入院2,4和6周时作简明精神病评定量表(BPRS)、护士用住院病人观察量表(NOSIE)及服药依从性评定。结果:患者在入院两周时的3项评定中,两组间均无显著性差异(P>0.05);4周时评定A组部分症状较B组改善明显,6周时评两组在BPRS、NOSIE及服药依从性方面均存在有显著性差异(P<0.05-0.01)。结论:认知治疗在精神分裂症缓解期可提高患者对疾病的认识能力,改善部分行为障碍;对提高病人服药依从性、巩固疗效、防止复发有良好效果。
  • 慢性肝炎患者心理障碍分析与治疗 免费阅读 下载全文
  • 由于慢性肝炎具有持续存在、反复发作及传染性等特点,慢性肝炎患者容易由疾病的挫折和冲突引起长期焦虑而出现以神经症为主要形式的心理障碍,表现为神经衰弱、焦虑神经症及恐怖症等。当慢性肝炎患者出现心理障碍时,一方面严重影响肝脏疾病的治疗与康复,另一方面可诱发心身疾病。因此,对慢性肝炎心理障碍患者进行心理治疗具有非常重要的意义。作者用个体心理疗法或行为疗法等对一些典型的慢性肝炎心理障碍患者,进行心理治疗,取得满意疗效。
  • 老年住院患者心理护理效果评估 免费阅读 下载全文
  • 高能聚焦超声无损伤肿瘤治疗仪用于肿瘤治疗的研究 免费阅读 下载全文
  • 针对高能聚焦超声在肿瘤治疗的应用过程中要解决的关键问题-成像、定位和聚焦及对关键问题常用的解决方法进行了简介,在进行比较的基础上选定了成像和聚焦解决方法;并在此基础上提出了一种高能聚焦超声肿瘤治疗仪的实现方案,对超声肿瘤治疗仪的关键部件治疗头部和臂部的结构结合实现功能进行了分析。分析了高能聚焦超声肿瘤治疗仪进行肿瘤治疗的过程:术前规划和手术模拟、术中定位和跟踪和术后治疗效果的评价。
  • 姑息治疗提高晚期癌症患者生活质量 免费阅读 下载全文
  • 目的:探讨应用姑息治疗对提高晚期癌症患者生活质量(quality of life,QOL)的影响。方法:对96例晚期癌症患者进行姑息治疗,采用QOL观察指标对本组病例治疗前、后评分,将QOL分为好≥41分;中21-40分;差≤20分共3个等级进行评估。结果:本组病例QOL评分,治疗前≤40分,治疗后≥41分者为71例;治疗前≤20分、治疗后≥21分者为12例;治疗前后无效者13例。QOL提高者占86%,无效为14%。结论:姑息治疗能提高晚期癌症患者的QOL。
  • 化疗辅助药物对卵巢癌患者癌因性疲乏的改善 免费阅读 下载全文
  • 目的:癌因性疲乏是生活质量的重要评估指标,观察应用化疗辅助药物对卵巢癌患者癌因性疲乏的改善作用。方法:对36例卵巢癌癌因性疲乏患者给予化疗辅助药物治疗观察癌因性疲乏和恶病质相关症状,并与27例对照组比较。结果:癌因性疲乏和恶病质相关症状改善显著,改善率分别为28%和52%-61%。结论:应用临床化疗辅助药物有助于治疗、改善癌因性疲乏与恶病质相关症状,可提高患者的生活质量。
  • 影响婴幼儿听力测试准确性的因素分析 免费阅读 下载全文
  • 右肺中心型肺癌致左下肢深静脉血栓治疗的循证医学病例分析 免费阅读 下载全文
  • 腭裂术后患者的语言功能训练 免费阅读 下载全文
  • 新生儿缺氧缺血性脑病55例的脑电图监测与预后评估 免费阅读 下载全文
  • 联合应用TCD和MRA对椎基底动脉缺血性眩晕的诊断价值 免费阅读 下载全文
  • 老年脑血管病与瞬目反射 免费阅读 下载全文
  • 目的:探讨老年脑血管病患者瞬目反射(BR)的改变及与临床表现的关系。方法:在眶上切迹处以脉冲方法电刺激眶上神经,用表面电极同时分别在双侧眼轮匝肌记录。一侧刺激同侧所记录到的2个波分别为R1,R2,刺激对侧所记录到的波为R2‘。结果:正常为11例,异常为25例。25例异常者中各成分异常率为R1:16%,R2:52%,R2‘:46%。结论:大脑半球的病变对BR是有影响的,主要表现在晚反应成分(R2,R2‘)上,呈现潜伏期延长、反应波幅降低或缺如,BR晚反应成分异常与偏瘫侧别有关,与是否存在面瘫及病变的大小、病灶的多少无明显关系。
  • 电刺激正中神经引发手肌反射对中枢神经病损的评定意义 免费阅读 下载全文
  • 目的:探讨手肌反射引发HR‘,LLR在中枢神经病损中的变化,揭示其作为诊断和康复评定的价值。方法:对45例确诊为脑血管意外偏瘫患者进行电刺激偏瘫手腕部正中神经,引发手肌(大鱼际肌)反射模式,测定HR‘,LLR的潜伏期、时限、波幅和分化的情况,与健手作对照,半年后再进行复查对照。结果:偏瘫手与健手HR‘的潜伏期、时限、波幅和分化差异均无显著性(P>0.05);偏瘫手LLR潜伏期延长,波幅降低,与健手对比差异均有非常显著性(P<0.01)。结论:电刺激正中神经引发手肌反射LLR的潜伏期、波幅和分化情况均能反映中枢神经的功能状态,并可作为中枢神经病损康复评定的客观定量指标。
  • 短暂性脑缺血30例神经图像检测价值 免费阅读 下载全文
  • 面神经麻痹肌电图及面神经传导速度的观察 免费阅读 下载全文
  • 肌电图对注射性坐骨神经损伤的诊断及康复评价 免费阅读 下载全文
  • 诱发电位对颈椎病颈部硬膜外腔注药治疗效果评定的价值 免费阅读 下载全文
  • 氟西汀对脑卒中抑郁患者不同时期神经功能康复的作用 免费阅读 下载全文
  • 目的:探讨氟西汀抗抑郁治疗对卒中后抑郁(Post-Stroke Depression,PSD)患者神经功能康复的影响。方法:选取经临床体格检查、头颅CT或MRI确诊的急性脑卒中患者132例(脑梗死78例,脑出血54例)。将符合DSM-Ⅳ抑郁症诊断标准的脑卒中患者随机分成抑郁治疗组和抑郁对照组,治疗组予氟西汀治疗。分别在病程2周、1月、3月、6月、12月时给每一位入组患者行神经功能缺损评分(SSS)、日常生活能力评分(ADL)、汉密尔顿抑郁量表(HAMD)、Zung‘s抑郁自评量表(SDS)和焦虑自评量表(SAS)评分。结果:脑卒中患者中的44.7%出现抑郁症状;抗抑郁药物PROZAC(盐酸氟西汀)能明显改善病程3,6月时神经功能缺损,病程12月时不仅抑郁症状减轻,ADL能力改善,神经功能缺损减轻尤为显著。结论:抗抑郁治疗能使PSD患者抑郁症状明显改善的同时,显著提高ADL能力和神经功能。
  • 微球制剂的给药途径及在医学康复的应用进展 免费阅读 下载全文
  • 近年来国内外微球制剂在靶向给药和非靶向给药等方面的微球制剂研制及临床应用的进展很快,尤其是在康复医学及康复肿瘤学中具有很大的应用价值。
  • 前列腺素E1对糖尿病痛性神经病变的疗效及安全性探讨 免费阅读 下载全文
  • A型肉毒毒素注射治疗面肌痉挛患者120例 免费阅读 下载全文
  • 石杉碱甲治疗阿尔茨海默病的临床疗效分析 免费阅读 下载全文
  • 降纤酶改善糖尿病性神经病变肢体感觉障碍43例疗效分析 免费阅读 下载全文
  • A型肉毒毒素治疗眼睑痉挛41例 免费阅读 下载全文
  • 万拉法新与阿米替林治疗抑郁症疗效对照分析 免费阅读 下载全文
  • 高压氧综合治疗多发性硬化54例 免费阅读 下载全文
  • 目的:探讨高压氧(HBO)对多发性硬化(MS)患者的临床疗效及其作用机制。方法:将102例多发性硬化患者的病情相匹配的原则分为高压氧综合治疗组54例和对照组48例,比较治疗前后有效率,影像学(CT,MR)的变化。结果:HRO综合治疗组的有效率,影像学好转率明显优于对照组(P<0.05)。结论:多发性硬化患者治疗时间越早越好,HBO可能是治疗MS的有效方法之一。
  • 高压氧治疗40例突发性耳聋时机与疗效的相关性 免费阅读 下载全文
  • 特定电磁波治疗仪与士的宁离子导入综合治疗面神经炎32例 免费阅读 下载全文
  • 对鼓浪屿海滨海水浴前后生化指标变化的观察与评价 免费阅读 下载全文
  • 纤维性颞下颌关节外强直康复治疗探讨 免费阅读 下载全文
  • 珠江三角洲地区温泉矿泉水治疗神经衰弱60例 免费阅读 下载全文
  • 高压氧综合治疗流行性乙型脑炎30例报告 免费阅读 下载全文
  • 低剂量照射脑垂体治疗老年前列腺增生症56例 免费阅读 下载全文
  • 随机单盲分组观察中药和激光血疗对血管性痴呆患者的效应 免费阅读 下载全文
  • 目的:研究弱激光血管内照射疗法及中药增智饮治疗血管性痴呆的疗效和对脑血流动力学的影响。方法:将120例血管性痴呆患者随机单盲分为3组,每组40例。研究组增智饮和激光血疗联用,对照组中药组单一应用增智饮,激光组单一应用激光血疗。结果:研究组治疗前后长谷川痴呆量表评分和大脑中动脉平均血流速度(Vm)比较差异非常显著(P<0.01),组间比较研究组智能评分和Vm参数与两对照组比较有显著性差异(P<0.05,P<0.01)。结论:激光血疗以及同时口服增智饮这种治疗方式治疗血管性痴呆可以明显地改善智能障碍和使大脑平均血流速度增加、脑血流改善。
  • 缺血性脑血管病中医辨证分型与血浆胃动素水平观察 免费阅读 下载全文
  • 目的:探讨血浆胃动素变化与急性脑血管病中医辨证分型的关系。方法:应用放射免疫测定法分别测定70例急性缺血性脑血管病患者和70例对照组入院后翌日、排便后翌日、病程等7天、病程第14天的血浆胃动素浓度,并分别进行组间比较。结果:急性缺血性脑血管病组的4次血浆胃动素含量均较对照组有显著升高(P<0.01);且急性缺血性脑血管病各中医证型中痰热腑实、风痰瘀阻型和痰湿蒙神型的血浆胃动素水平较对照组升高意义显著(P<0.01),随着病情好转胃动素水平逐渐降低。结论:初步为急性缺血性脑血管病中医的辨证分型,特别是痰热腑实等证型的确定及通腑药的合理应用提供一个客观指标,将充实和完善缺血性脑血管病的辨治理论。
  • 推拿治疗2型糖尿病疗效分析 免费阅读 下载全文
  • 目的:2型糖尿病的治疗一般采用药物治疗、饮食控制及运动疗法。传统推拿法治疗2型糖尿病已在临床开展。本研究的目的是为了观察本疗法在可控制条件下的有效性。方法:采用药物配合推拿(观察组)治疗237例2型糖尿病,并设药物组(对照组)治疗219例2型糖尿病。结果:观察组总有效率89.5%,对照组总有效率78.5%。结论:推拿配合药物治疗2型糖尿病从临床观察疗效肯定。
  • 护理指导对类风湿关节炎患者实施疾病分期功能康复训练的工作特征 免费阅读 下载全文
  • 周围性面瘫恒定磁场治疗中的面肌功能训练 免费阅读 下载全文
  • Establishment of rabbit model of cerebral infarction for interventional treatment 免费阅读 下载全文
  • AIM:To establish a model of cerebral infarction in order to study the interventional treatment.METHODS:An improved 3.0F SP Cobra catheter was introduced to the internal carotid artery by puncturing the femoral artery.After intemal carotid arteriography thrombus was injected to embolize its MCA.3 hours later,clinic observe and computed tomography was examined to analyze results.RESULTS:Clinic observation confirmed that the rabbit had some nerve defect symptoms and CT exam proved cerebral infarction.CONCLUSION;This technique is convenient for application and the model can meet the standard of study of clinical interventional treatment.
  • Effects of early rehabilitation to patients with paralysis after cerebral infarction 免费阅读 下载全文
  • It is considered now that early rehabilitation interventional mechanism is related to the plasticity of brain that means after injury of neural function,cental nervous system has the ability of compensation and functional recombination.OBJECTIVE:To explore the effects of early rehabilitation on paralysis after cerebral infarction.
  • Cellular uptaking rate and subcellular distribution of thiooligonucleotide which can inhibit cerebral thrombosis 免费阅读 下载全文
  • AIM:To explore the membrane permeability,enzyme tolerance,and stability of phosphorothioate oligodeoxynucleotide(P-ODN) which can inhibit cerebral thrombosis.METHODS:(1)Oligodeoxynucleotide was synthesized with phosphoramidite method in solid phase,3‘ end was modified with thiophosphoter.(2)Uptake and subcellular distribution of P-ODN.P-ODN was given directly.We observed total uptake rate of P-ODN by ECV304 cells and subcellular distribution of P-ODN.RESULTS:(1)ECV cells uptake more P-ODN with increase of concentration,the uptake rate was about 10.8%-11.9%.(2)Subcellular distribution of P-ODN:P-ODN was mainly distributed in nucleus especially nucleus sediments(69.3%-77.2%)(p<0.05).CONCLUSION:P-ODN suppressing cerebral thrombosis has favorable transmembrane ability,enzyme resistance and stability.
  • The rehabilitation effect of blood therapy after laser magnetization on patients with stroke 免费阅读 下载全文
  • There are lots of methods for curing stroke now but the effect of function al rehabilitation is different.This paper deals with the rehabilitation effect of blood therapy after laser magnetization on patients with stroke.OBJECTIVE:To investigate the rehabilitation effect of blood therapy after laser magnetization on patients with stroke.UNIT:Department of Internal Medicine,Central Hospital of Jinzhou City.RESULTS:In treatment group,62 cases achieved recovery (64.6%),10cases achieved obvious effect(10.4%),18 cases achieved effect(18%) and 6 cases achieved no effect(6.3).The total effective rate was 93.8%;In control group,38 cases achieved recovery(39.6%),19 cases achieved obvious effect(20.0%),27 cases achieved effect(28.1%) cases achieved no effect(12.5%).The total effective rate was 87.5%.There were obvious differences between two groups(P<0.01).DISCUSSION:The blood therapy after laser magnetization can accelerate erythropoiesis,quickly improve saturation of blood oxygen and partial pressure of oxygen and improve state of anoxia of brain and factilitate recovery of cerebral function.
  • Application of Massage in rehabilitation of moter function in stroke 免费阅读 下载全文
  • Massage has become a manipulation of physical therapy in recent years.Massage is based on theory of zang and fu,channel and collateral of traditional Chinese medicine,instructed by pathology,anatomy and diagnosis of western medicine and combined with kinds of massage manipulation all which have make it an important method of nondrug therapy in preventing and treatment of diseases.Massage is also a measure in rehabilitation of motion function of patients with stroke^[1].
  • The protection effectiveness of the expression of heat shock protein on ischemic brain damage 免费阅读 下载全文
  • Heat shock protein is a group of stress protein produced under ill state.It can protect normal cells from damages caused by had stimulates.It is thought as one of substance basis that remain in the process of evolution and take effect of anti-damage.Now it is paid attentions as neuron protective substance induced by cerebral ischemic preconditioning.
  • The relativity of the activity change of tissue—type plasminogen activator and type 1 plasminogen activator inhibitor in patients with cerebral infarction and defect of nerve function 免费阅读 下载全文
  • AIM:To explore the dynamic changes of the activity of tissue-type plasminogen activator(t-PA) and type 1 plasminogen activator inhibitor (PAI-1) and its clinical significance by observing the activity of t-PA and PAI-1 in patients in acute and recovery phases of arteriosclerotic cerebral infarction.METHODS:Testing the activity of plasme t-PA and PAI-1 of 91 patients with arteriosclerotic cerebral infarction and 80 healthy old ages by Chromgenic substrate methods and controlling them.RESULTS:The activity of t-PA in acute and recovery stage of arteriosclerotic cerebral infarction patients were apparently lower than that of control and the activity of PAI-1 were higher than that of control.volume of cerebral infarction was negatively related to the activity of t-PA and positively related to the activity of PAI-1.CONCLUSION:The plasma fibrinolytic activities of the acute and recovery stage patients with arteriosclerotic cerebral infarction declined.
  • Effect of the antibody of brain—derived neurotrophic factor on the rat with ischemic injury from obstruction of middle cerebral artery 免费阅读 下载全文
  • AIM:To observe the effect of the antibody of brain-derived neurotrophic factor (BDNF) by cortical microinjection on hippocampal ischemic injury rats.METHODS:Preparation of local cerebral ischemic-reperfusion injury model:cortical stereostaxic approach,microinjection of BDNF antibody.Applied immunohistochemical method to observe distribution of BDNF in cortex after injection of the antibody,to observe the alteration of ischemic injury between control group and BDNF antibody group.RESULT:The volume of cerebral infarction in BDNF antibody group was larger than control group.CONCLUSION:BDNF has protection function for cerebral ischemia.
  • Rehabilitation therapy centralized on facilitation and acupuncture on upper extremities spasm after stroke 免费阅读 下载全文
  • AIM:To observe the therapeutic effect of rehabilitation therspy centralized on facilitation and acupuncture on upper extrmilies spasm after stroke.METHODS:56 cases of stroke patients with upper extremities spasm were divided into two groups by random.28 patients in treatment group were received rehabilitation therapy centralized on facilitation and acupuncture treatment.Others in control group were received traditional method.RESULT:All patients were evaluated by muscle tone evalustion of Ashworth Scale.The outcomes of two groups has significant different(P<0.01).CONCLUSION:We could archive the satisfactory effects with acupuncture and rehabilitation therapy centralized on facilitation on upper extremities spasm of stroke patients.
  • The effect of Naofusu on neural function recovery of patient with stroke 免费阅读 下载全文
  • Brain infarction is the most common type of ischemic cerebrovascular disease in disease incidence,which can cause the defection of neural function.OBJECTIVE:To investigate the rehabilitation effect of naofusu on stroke.
  • The reasons analysis of failure in rehabilitation treatment of senile patients after stroke 免费阅读 下载全文
  • The disablement rate of patients after stroke remains high,which perhaps is associated with the factor that many patients cannot get timely and reasonable rehabilitation treatment and the factor the some medical staff pay attention to treatment but ignore early rehabilitation treatment.OBJECTIVE:To analyze the reason of failure in rehabilitation treatment of senile patients with stroke.UNIT:Department of Rehabilitation,Affiliated Jinshan Hospital of Fudan University.SUBJECTS:There were 24 patients recruited from June 2001 to May 2002,which were diagnosed as hemiparalysis after stroke.All the patients failed in accepting rehabilitation treatment.Among the patients,there were 20 males and 4 females,aged 60 to 80 years (average 65).There were 8 cases of brain hemorrhage and 16 cases of brain infarction.The patients accepted rehabilitation treatment 10 to 28 days after stroke.The time of rehabilitation treatment was 2 to 67 days(average 17).The muscular strength of all the patients was less than grade 3.INTERVENTION:To find out the reasons of failure in the rehabilitation treatment.RESULTS:The patients failing in the rehabilitation treatment because of healthy factors accounted for 40%;That because of family ties and experimental factors accounted for 30%;That because of the prejudice for clinical medicine accounted for 10%.CONCLUSION:The senile patients with stroke perhaps has had coronary heart disease,hypertentive heart disease and hypertension et al before having stroke,which causes decreasing of cardiacfunction and even less quantity of exercise also can lead to the exacerbation of symptoms such as chest distress,vertigo and short breath.Besides,compensation of elderly patients decreased and the patients cannot adapt to rehabilitation training.
  • The acupuncture therapy and auricular—plaster therapy on 22 patients with stubborn hiccup after stroke 免费阅读 下载全文
  • The patients with acute cerebral infarction often suffer from stubborn hiccup and are difficult to cure.OBJECTIVE:To observe the effect of acupuncture therapy and auricular-plaster therapy on the patients with stubborn hiccup after acute cerebral infarction.
  • Neuropsychic symptoms treatment by hyperbaric oxygen combined with cytidine diphosphate ethanolamine in 89 cases of hypnotic poisoning 免费阅读 下载全文
  • With developing of therapeutic condition and level,mortality of hypnotic poisoning had been reduced greatly.But due to different metabolic half time and individual variation,neurospychic symptoms might existed for one or two weeks after treatment by simple drug therapy.OBJECTIVE:To investigate the therapeutic effect of hyperbaric oxygen combined with cytidine diphosphate ethanolamine in treatment of hypnotic poisoning.
  • Effect of early rehabilitation nursing on ability of daily living in patients with stroke 免费阅读 下载全文
  • The direction of modern research on rehabilitation is to recover the function,and improve patients‘ motion,living ability,make them turn round to family and society.OBJECTIVE:To explore the effect of early rehabilitation nursing on ability of daily living of patients with stroke.
  • Rehabilitation nursing experiences of patients with paralysis after stroke 免费阅读 下载全文
  • Because disease course of stroke was long,directed nursing was undertaken to different mental and physiological manifestations to restore function at maximal degree and reduce incidence of disability.OBJECTIVE:To explore rehabilitation nursing methods to patients with paralysis after stroke.
  • Effect of early rehabilitation training on aphasia after stroke 免费阅读 下载全文
  • Stroke is the main reason of aphasia which etiology is very complicated and living quality of patients is often affected.Language trainning has an important significance for patients of return to society.OBJECTIVE:To exprole the effect of early rehabilitation training on aphasia after stroke.
  • Effect of rehabilitation nursing on recovery of linguistic function in stroke aphasia 免费阅读 下载全文
  • Labopathy complicated in stroke can recovery or be restored by linguistic corrective training.OBJECTIVE:To observe the effect of rehabilitation nursing on recovery of linguistic function in stroke aphasia.
  • Relationships between angiotensin—converting enzyme gene polymorphism and lacunar infarction in early stage of essential hypertension 免费阅读 下载全文
  • AIM:To investigate the relationships between angiotensin-converting enzyme gene polymorphism and lacunar infarction in patients with essential hypertension.METHODS:Polymeras chain reaction(PCR) was used to determine the genotypes for an insertion/deletion polymorphism of 287 pb fragment of ACE gene in 50 healthy persons,50 patients with simple essential hyperten sion and 30 patients with essential hypertension and lacunar infarction.RESULTS:There was no significant difference of genotype and allele between healthy persons and patients with simple essential hypertension;but there was significant difference of D allele and DD genotype of ACE gene between esential hypertensive patients with lacunar infarction and patients with simple essential hypertension and healthy persons.CONCLUSION:There is a significant relation between ACE gene polymorphism and essential hypertensive patients with lacunar infarction.
  • Diet therapy of chronic renal failure 免费阅读 下载全文
  • The effect of seawater bath on 30 patients with hyperlipemis 免费阅读 下载全文
  • The therapy of seawater bath can make the speed of fat oxidation by body tissue and liver faster and has a better curative effect on the patients with hyperlipemia and hypertension.Hyperlipemia do harm to severely the health of middle-aged and elders and can cause hypertension and coronary heart disease.The treatment of sea bath can make 80% cholesterol become cholic acid in liver and at last bile salt,which is drained with bile to intestines.HDL-C is demomposed with the consumption of TC and TG,which showes the trendency of gradually in creasing in content and helps cleaning fat rubbish.OBJECTIVE:To observe the effect of seawater bath on the patients with hyperlipemia.
  • Diagnosis and treatment of 20 cases of phenylpyruvic oligophrenia 免费阅读 下载全文
  • Phenylpyruvic oligophrenia (Folling‘s disease)is one of seldom treatable genetic metabolic diseases and early diagnosis and treatment were the key to avoid irreversible injury of nerve system.OBJECTIVE:To explore the diagnosis and treatment of phenylpyruvic oligophrenia.
  • Inducing of channels,collateral and acupoints combined with modern rehabilitation technology on 68 cases of cerebral paralysis 免费阅读 下载全文
  • In our country,inducing of channel,collateral and acupoint,acupuncture and moxibustion,massage,Chinese herbs are therapeutic methods of traditional Chinese medicine on cerebral paralysis and function training is the method of western medicine such as Tian therapy.According to the correlation channel and collateral theory of traditional Chinese medicine and neural physiology,There are complementary actions when these two methods are combined.OBJECTIVE:Inducing of channels and collateral combined and modern rehabilitation technology were combined in treatment of 68 cases of cerebral paralysis to explore its practical value.
  • Rehabilitation effect of atropine depressed therapy on amblyopia in children 免费阅读 下载全文
  • The process of treating amblyopia is to create good development condictions for eyes of amblyopia so as to eyes of amblyopia and dominant eyes can grow successively.OBJECTIVE:To explore rehabilitation effect of Atropine depressed therapy on amblyopia of children.
  • The effect of life events,personality and coping stratedies on depressive of undergraduates 免费阅读 下载全文
  • AIM:To study the effect of life events,personality and coping strategies on depression of undergraduates.METHOD:fifteen hundred students were selected in the three schoolyards of Central South University.Life Events Scale,Coping Strategies Scale,Eysenck Personality Questionnaire(EPQ) and Self-rating Depressive Scale (SDS) were used to assess all samples.RESULTS:The score of SDS was (42±8).The life events came from relationship of person,stress of study,loss,punishment,health and adaptation,love and family were higher in the SDS group of higher score,which the SDS group of higher score took more negative coping strategies than the normal score.CONCLUSION:The rate of depression was higher in undergraduates,which need more attention on it.More life ovents,introversive instability personality and negative coping strategies may be the main risk factors that caused depression.
  • Evaluating the effectiveness of hospitalized occupational rehabilitation on social functioning in chronic schizophrenic patients 免费阅读 下载全文
  • AIM:To evaluate the effectiveness of hospitalized occupational rehabilitation for chronic schizophrenic patients of social functioning.METHODS:79 qualified cases were selected from chronic psychiatric inpatient departments,divided into two groups randomly,of which 45 cases of treatment group accepted hospitalized occupational rehabilitation,another 34 cases of control group accepted ordinary treatement.social functioning was evaluated by the Scale of Social Skills of Chronic Schizophrenic In-patients(SSSI).RESULTS:6-month-course of research figured out that the rank of improvement of the total disability degree of the treatment was significantly larger than that of the control group(P<0.05).Items of which rank of improvement of the treatment was significantly larger than those of the control group are participating in the occupational rehabilitation,social withdraw and concern and care about others(P<0.01-0.05).The level of disability of 55.6% of the treatment decreased more than that of the control(26.5%)(P<0.05) evaluated by SSSI.CONCLUSION:Hospitalized occupational rehabilitation is effective in improving social functioning of chronic schizophrenic patients,especially in improving items like participating in the occupational rehabilitation,social withdraw and concern and care about others.
  • Effects of mental intervention on cervical vertigo 免费阅读 下载全文
  • Cervical Vertigo(CV)belongs to vertebral artery type of cervical spondylopathy which clinical manifestation was paroxysmal vertigo and is highly related to cervical motion.Recent clinical experiences proved that conprehensive treatment was superior to simple treatment.Because of patients were in different departments,therapeutic methods were also different,effects produce slowly,remote effects were not obvious and recurrence rate was higher.OBJECTIVE:To observe immediate effects of comprehensive treatment on cervical vertigo and remote recurrence rate.
  • SCL—90 evaluation of matermity blues and associated factors analysis 免费阅读 下载全文
  • Matermity blues(MB) refer to short and slight emotional pain or transient state of crying and depression.New many studies have shown that there is closed association between the occurrence of MB and psychological and social factors and obstetric factors.OBJECTIVE:To investigate the effect of psychotherapy on matermity blues.
  • Investigation and analysis of conditions of 202 psychotics with long—term hospitalization 免费阅读 下载全文
  • Reports about average life span of psychotics are different,generally 3/4 of normal people.Rongfu soldiers mental hospital of Shanxi mainly treats psychotics who were all returning soldiers in glory.Analysis to patients with long hospitalization will do good to summing up experiences and do better service to patients.OBJECTIVE:To investigate and analyze conditions of 202 psychotics from 1954 to 2001.
  • Prevention and rehabilitation treatment of osteoporosis 免费阅读 下载全文
  • Incidence of osteoporosis is very high in menopausal women and the senile.There weren‘t satisfkying therapeutic method at present and exercises,diet,shinning,drugs were the main basic treatment for osteoporosis which proventive effects were better than therapeutic effects.Scientific exercises plus diet containing high calcium or suitable supplement of calcium is an effective preventive method for osteoporosis.
  • Rehabilitation and treatment of senile osteoporosis 免费阅读 下载全文
  • When human got aged(>60 years old),body will get shorten,aching back was often observed and fracture occurred easily by a minor force which were mainly led to by osteoporosis.So,etiology of senile osteoporosis,its rehabilitation and treatment were introduced in this article.
  • Rehabiltation training of patients with dysphagia after maxillofacial trauma 免费阅读 下载全文
  • In maxillofacial trauma,food-taking don‘t affect healing of wound.If patients don‘t take food as early as possible and oral cavity is often kept in stable condition,oral cavity will become a hot bed for microorganisms such as bacteris.OBJECTIVE:To explore the effect of rehabilitation training on dysphagia after maxillofacial trauma.
  • Experience of preoperative and postoperative rehabilitation care to cataract patients 免费阅读 下载全文
  • Preoperative and postoperative rehabilitation care is very important to the cataract patients under operation,especially if the patients affected with the other kinds of senile disease of if they are old patients.OBJECTIVE:To study the importance of preoperative and postoperative rehabilitation care on the recovery or improvement of the patients‘ eyesight.
  • Early rehabilitation for nasopharyngeal carcinoma patients who received radiotherapy 免费阅读 下载全文
  • Rehabilitation of mental disturbance in patients with stroke
    Utilization of systemic planned health education in the rehabilitation of hypertension patients
    Correlation research between the patients with cerebral infarction in different ages and blood lipid levels
    Clinical analysis of 52 cases of epilepsy after stroke
    Alternation of plasma c-type natriuretic peptide in cerebral infarction
    The protective effect of subhypothermiaon brain of patient with ischemic cerebrovascular disease on different time
    The recovery comparison of comprehensive rehabilitation and simple pharmacotherapy on the patients after stroke during the period of sequela
    Rehabilitation treatment of dysphagia in 81 cases of stroke
    The principle analysis of rehabilitation on 46 patients with cerebrovascular disease and secondary epilepsy
    Linguistic rehabilitation nursing of pregnancy-induced hypertension syndrome associated with cerebral hemorrhage
    The effect of early enteral nutritive support on patients after esophageal and gastric operation
    Infertious risk factors analysis to senile patients with diabetes
    Radioimmunological analysis of pressure regulating substances and their relationship with primary and renal hypertension
    Influence of changing bad living habits on blood pressure control of hypertension patients
    Electrocardiogram reaction of coronary heart disease after hyperbaric oxygen treatment
    Preoperative psychoanalysis and nursing measures of senior patients with coronary heart disease in intervening treatment
    Report of 2 cases with brachium potine syndrome
    The protective effect of ischemic preconditioning occur in patients with acute myocardiac infarction
    Foot nursing of patients with diabetes
    The rehabilitation effect of hyperbaric oxygenation on new-born with hypoxic and ischemic encephalopathy
    External washing therakpy of traditional Chinese medicine to children's cerebral hypermyotonia
    Analysis of mental health of students defeated in college entrance examination
    The analysis of depression in aged patients with myocardial infarction and its elative factors
    Mental nursing of community patients with psychosis in recovery stage
    The survey of the relationship between osteoporosis and relative effective factors in old men
    Voice training to palatoschisis children
    Rehabilitative treatment of senile osteoporosis fracture
    Effect evaluation of artemisia desertorum spreng on ability of daily life after extraction of impacted tooth
    The causes of thyreoprival hoarseness and rehabilitation
    Construction of adenoviral vector for luciferase driven by hTERT core promoter modified with MYC-responsive elements
    物理医学与数字化虚拟人体的实践前景(钟世镇 原林 等)
    心脏康复研究的最新进展(张宝慧)
    组织化卒中医疗的概念及国内外特征(王拥军)
    循证医学在康复临床中的应用(何成奇 丁明甫)
    刘海若重症复合性损伤的康复问题(王茂斌 高谦 等)
    糖尿病患者的康复治疗与评定(吴毅 孙莉敏 等)
    教育、职业与痴呆流行性的关系
    血管性痴呆患者的行为问题作为功能能力的预测指标
    血管性痴呆患者MRI皮层下高密度和脑容积与认知功能的关系
    白质损伤、定量磁共振成像及痴呆
    早期炎症与痴呆的关系
    痴呆患者死亡的预测指标
    采用视觉联合检测Alzheimer型早期痴呆
    痴呆患者抑郁综合征及脑综合征的关系
    老年高血压与Alzheimer病、血管性痴呆和认识功能的关系
    糖尿病与痴呆、Alzheimer病及血管性认知障碍的关系
    加兰他敏治疗阿尔茨海默(Alzheimer)病(OlinJ SchneiderL)
    吡拉西坦对痴呆及认知障碍的效果(FlickerL GrimleyEvansJ)
    卵磷脂治疗痴呆及认知障碍(HigginsJPT FlickerL)
    statins预防阿尔茨海默(Alzheimer)病(ScottHD LaakeK)
    维生素E治疗阿尔茨海默(Alzheimer)病(TabetN BirksJ)
    阿司匹林治疗血管性痴呆(WilliamsPS RandsG)
    定位力检测对痴呆患者认知及行为能力的影响(SpectorA OrrellM 等)
    消炎痛治疗阿尔茨海默(Alzheimer)病(TabetN FeldmanH)
    高血压和高胆固醇血症是引起老年痴呆病的两大危险因素
    早老性痴呆症早期诊断新法
    预测阿尔茨海默病发病有新法
    老年性痴呆的国际疾病诊断标准
    痴呆病人出现精神症状时药物的选择
    帕金森病与滥用药物有关
    雌激素可防止或延缓早老性痴呆
    老年人步态异常有助于预测非阿尔茨海默病(Alzheimer)性痴呆症的发生
    老年痴呆新基因位点发现
    中医防治脑衰老的新理论
    痴呆症又有新说法
    老年人中度高血压对认知功能有益
    使用抗炎药物可减少患阿尔海默氏病的危险
    阿尔茨海默病的保护因素——运动和户外活动(洪震 周玢 等)
    单光子计算机断层扫描对单侧脑梗死早期持续康复治疗后脑功能活动状态研究(李刚 厉启松 等)
    高血压患者心理卫生状态与生活满意度的关系
    超声乳化白内障吸除术后和囊外白内障摘除术后视功能比较(刘杰为 许京京 等)
    运动康复促进脑梗死大鼠学习记忆功能恢复的研究(余茜 李晓红)
    垂体腺苷环化酶激活肽对缺血再灌注脑神经元凋亡的作用(刘宪霜 崔旭 等)
    雌二醇对拟痴呆小鼠学习记忆功能的影响(顾晓胜 沈楠 等)
    DCG—Ⅳ在大鼠脑损伤及二次脑损伤中的神经保护作用(公方和 费舟 等)
    2型糖尿病患者血清瘦素水平的分析(谢娟 郭刚 等)
    下颌骨牵张成骨和牵张器拆除时机的评价(刘彦普 邵桢 等)
    脑血管血液动力学检测在脑血管病防治中的应用价值(黄久仪 王桂清 等)
    脑卒中的基因治疗(曾现伟 沈建康)
    帕金森病患者的健康相关生活质量及其影响因素(陈圣鑫 陈生弟)
    炎性细胞因子与脑缺血(屠永华 李岚)
    小GTP蛋白Rho家族在神经损伤修复中的作用机制
    脑卒中患者损伤部位与功能预后的关系(姜永梅 刘世文 等)
    雌激素及植物雌激素治疗老年性痴呆的研究现状(崔建庄 毕淑琴)
    脑血管病吞咽障碍的康复评定(桑德春 朴春花)
    从循证医学角度谈中医药防治脑卒中的研究(高颖 王永炎)
    腹针对脑卒中患者的康复作用(马林儒 黄飞龙 等)
    不同类型失语症的康复训练技术(罗少丽)
    脑卒中患者运动疗法治疗前后的肌张力(李积荣 苗建亭 等)
    脑卒中早期实施医疗体育训练248例(赵美玉)
    氟西汀治疗血管性抑郁症(鲁广秀)
    脑卒中2例康复治疗体会及效果分析(涂靖)
    脑梗死偏瘫患者康复与单纯药物治疗160例肢体功能恢复效果比较(车玉民 杨东妮 等)
    冬季性抑郁对脑卒中患者Barthel指数的影响(张钦昌 杨朴 等)
    急性脑梗死患者患肢肌张力出现时间对功能重建的影响(王俊卿 周筱燕 等)
    固定位训练并用气血循环机对脑卒中肩痛的防治作用(张国印 刘剑)
    A型肉毒毒素肌肉注射治疗脑血管病后肢体痉挛36例(单丽娟 刘慧敏 等)
    减重踩车训练对脑卒中偏瘫患者步态的影响(陈尚康 关晨霞 等)
    关于进一步加强残疾人康复工作的意见
    慢性心力衰竭患者运动耐力改变及运动处方研究现状(朱起东 史长河 等)
    急性心肌梗死患者心脏康复时应用早期活动5级法的评价(刘志红 李玉泽)
    急性心肌梗死7例2周康复训练效果分析(段霄燕)
    雾化吸入爱喘乐对慢性阻塞性肺疾病肺功能的影响(田军)
    步行运动对2型糖尿病患者血糖、血脂的影响
    心脑宁治疗糖尿病合并抑郁症的疗效观察(陈超)
    糖尿病患者血清骨钙素和骨矿含量变化的分析(于青琳 于庆潭)
    运动疗法对妊娠糖尿病的影响(屠霞芬 陈文华 等)
    女性易抑郁与基因有关
    原发性骨质疏松症诊断技术的临床应用评价
    中医通补法治疗原发性骨质疏松症的作用机制研究(周丽珍 马元)
    中医药防治骨质疏松症研究现状(蓝群 何成奇 等)
    脑性瘫痪高患病率胎尸脑血管临床解剖学特征(高晓群 付春景 等)
    高危儿监测与脑性瘫痪的早期诊断(刘芸 李丽君 等)
    病毒性脑炎患儿肌力和语言功能恢复30例报告(冉茂群 李帮惠 等)
    心理干预和暗示治疗儿童癔症(安金斗)
    军医大学研究生心理健康与人格特征分析(汪涛 韩爱华 等)
    心理精神疾病患者睡眠型态紊乱的心理行为干预(张淑兰 安俊峰 等)
    城市与农村精神分裂症患者的家庭负担(郭建雄 肖爱祥 等)
    提高精神病患者家庭社会处境的调查研究(张仲荣)
    精神病患者的生活质量与社会支持的关系(潘润德 潘天伟)
    工娱疗法辅助利培酮改善精神分裂症阴性症状43例(邢秀娟 汪灵芝 等)
    抑郁症患者自评生活满意度和痊愈状况分析(李彩霞 郭本玉 等)
    儿童精神分裂症特征分析132例2年随访(郭本玉 季卫东)
    心理康复教育在甲状腺功能亢进患者接受^131I治疗中的作用(罗俊敏)
    精神分裂症后抑郁患者支持性心理治疗34例(李秀荣 吴士玲)
    酒精所致精神障碍患者疾病知识的掌握情况(张瑞珍 薛继芳 等)
    认知治疗改善精神分裂症患者认识及部分行为能力的作用(王勇)
    慢性肝炎患者心理障碍分析与治疗(李跃旗 孙惠莉 等)
    老年住院患者心理护理效果评估(冯永林 何敏慧 等)
    高能聚焦超声无损伤肿瘤治疗仪用于肿瘤治疗的研究(项林清 马培荪 等)
    姑息治疗提高晚期癌症患者生活质量(赵勤)
    化疗辅助药物对卵巢癌患者癌因性疲乏的改善(夏志军 张淑兰 等)
    影响婴幼儿听力测试准确性的因素分析(姜苏敏)
    右肺中心型肺癌致左下肢深静脉血栓治疗的循证医学病例分析(谢晓冬 刘永叶 等)
    腭裂术后患者的语言功能训练(张永红 苏健 等)
    新生儿缺氧缺血性脑病55例的脑电图监测与预后评估(孙虹 王倩 等)
    联合应用TCD和MRA对椎基底动脉缺血性眩晕的诊断价值
    老年脑血管病与瞬目反射(董艳娟 王苏 等)
    电刺激正中神经引发手肌反射对中枢神经病损的评定意义(梁镇宏 王汉明 等)
    短暂性脑缺血30例神经图像检测价值(王顺华)
    面神经麻痹肌电图及面神经传导速度的观察(叶爱萍)
    肌电图对注射性坐骨神经损伤的诊断及康复评价(李晖)
    诱发电位对颈椎病颈部硬膜外腔注药治疗效果评定的价值(宋品 李军 等)
    氟西汀对脑卒中抑郁患者不同时期神经功能康复的作用(程丰 邵国富 等)
    微球制剂的给药途径及在医学康复的应用进展(封兴华)
    前列腺素E1对糖尿病痛性神经病变的疗效及安全性探讨(张曼华 李娜 等)
    A型肉毒毒素注射治疗面肌痉挛患者120例(席刚明 何国厚 等)
    石杉碱甲治疗阿尔茨海默病的临床疗效分析(宋志宇 卢宏)
    降纤酶改善糖尿病性神经病变肢体感觉障碍43例疗效分析(卢莹)
    A型肉毒毒素治疗眼睑痉挛41例(曲芳 孙英健 等)
    万拉法新与阿米替林治疗抑郁症疗效对照分析(陈恩民)
    高压氧综合治疗多发性硬化54例(潘贺葵 李东娟 等)
    高压氧治疗40例突发性耳聋时机与疗效的相关性(原毅 李颖 等)
    特定电磁波治疗仪与士的宁离子导入综合治疗面神经炎32例(田雅萍 兰怡 等)
    对鼓浪屿海滨海水浴前后生化指标变化的观察与评价(赵明国 邓群英 等)
    纤维性颞下颌关节外强直康复治疗探讨
    珠江三角洲地区温泉矿泉水治疗神经衰弱60例(何本夫 罗磊 等)
    高压氧综合治疗流行性乙型脑炎30例报告
    低剂量照射脑垂体治疗老年前列腺增生症56例(冯济龙 黄立新 等)
    随机单盲分组观察中药和激光血疗对血管性痴呆患者的效应(徐志坚)
    缺血性脑血管病中医辨证分型与血浆胃动素水平观察(刘泰 曾祥发 等)
    推拿治疗2型糖尿病疗效分析(章家福)
    护理指导对类风湿关节炎患者实施疾病分期功能康复训练的工作特征(张丽娟)
    周围性面瘫恒定磁场治疗中的面肌功能训练(麻明歌 李平 等)
    Establishment of rabbit model of cerebral infarction for interventional treatment
    Effects of early rehabilitation to patients with paralysis after cerebral infarction(许艳芳 刘姝娜)
    Cellular uptaking rate and subcellular distribution of thiooligonucleotide which can inhibit cerebral thrombosis
    The rehabilitation effect of blood therapy after laser magnetization on patients with stroke
    Application of Massage in rehabilitation of moter function in stroke
    The protection effectiveness of the expression of heat shock protein on ischemic brain damage
    The relativity of the activity change of tissue—type plasminogen activator and type 1 plasminogen activator inhibitor in patients with cerebral infarction and defect of nerve function(杜小平 张乐 等)
    Effect of the antibody of brain—derived neurotrophic factor on the rat with ischemic injury from obstruction of middle cerebral artery
    Rehabilitation therapy centralized on facilitation and acupuncture on upper extremities spasm after stroke
    The effect of Naofusu on neural function recovery of patient with stroke
    The reasons analysis of failure in rehabilitation treatment of senile patients after stroke(邹菊培 杨颖)
    The acupuncture therapy and auricular—plaster therapy on 22 patients with stubborn hiccup after stroke(代英杰 张尔红 等)
    Neuropsychic symptoms treatment by hyperbaric oxygen combined with cytidine diphosphate ethanolamine in 89 cases of hypnotic poisoning(刘洪杰 马佰恩)
    Effect of early rehabilitation nursing on ability of daily living in patients with stroke
    Rehabilitation nursing experiences of patients with paralysis after stroke(孙静敏)
    Effect of early rehabilitation training on aphasia after stroke(郭春燕 周晔 等)
    Effect of rehabilitation nursing on recovery of linguistic function in stroke aphasia
    Relationships between angiotensin—converting enzyme gene polymorphism and lacunar infarction in early stage of essential hypertension
    Diet therapy of chronic renal failure
    The effect of seawater bath on 30 patients with hyperlipemis(沈淑花)
    Diagnosis and treatment of 20 cases of phenylpyruvic oligophrenia(周丽娟 庞雪晶 等)
    Inducing of channels,collateral and acupoints combined with modern rehabilitation technology on 68 cases of cerebral paralysis
    Rehabilitation effect of atropine depressed therapy on amblyopia in children(徐艳丽)
    The effect of life events,personality and coping stratedies on depressive of undergraduates
    Evaluating the effectiveness of hospitalized occupational rehabilitation on social functioning in chronic schizophrenic patients
    Effects of mental intervention on cervical vertigo(曾西 陈尚康 等)
    SCL—90 evaluation of matermity blues and associated factors analysis
    Investigation and analysis of conditions of 202 psychotics with long—term hospitalization(武克文 杨文丽)
    Prevention and rehabilitation treatment of osteoporosis(单述刚 段献荣)
    Rehabilitation and treatment of senile osteoporosis(张富强)
    Rehabiltation training of patients with dysphagia after maxillofacial trauma(王军 林健)
    Experience of preoperative and postoperative rehabilitation care to cataract patients
    Early rehabilitation for nasopharyngeal carcinoma patients who received radiotherapy(朱巧凤)
    《中国临床康复》封面

    主管单位:中华人民共和国卫生部

    主办单位:中国康复医学会

    社  长:王莉莎

    主  编:刘昆

    地  址:沈阳1200邮政信箱

    邮政编码:110004

    电  话:024-23384352 23394178

    电子邮件:[email protected]

    国际标准刊号:issn 1671-5926

    国内统一刊号:cn 21-1470/r

    邮发代号:8-587

    单  价:15.00

    定  价:780.00